Pulmonary Complications of Liver Disease

  • Mercedes Susan Mandell
  • Masahiko Taniguchi


Liver disease affects the function of all other organ systems and can be thought of as a systemic disease that results in multisystem organ failure as a principal cause of death. The lung is particularly sensitive to changes in hepatic function and respiratory failure is a common complication of advanced liver disease. Historically, physicians considered the association between lung and liver disease to be rare. But more recent studies have shown that symptoms such as hypoxemia at rest occur in at least 27–33% of liver transplant candidates [1]. Hypoxemia is caused by a wide variety of diseases. Some pulmonary diseases occur more commonly in patients with liver disease than in the general population. These pulmonary defects can affect the perioperative management of patients and may influence the decision to proceed with transplantation. This chapter will present an overview of the changes in lung mechanics and gas exchange that occur in patients with liver disease and...


Respiratory failure Hepato-pulmonary syndrome Porto-pulmonary hypertension Restrictive lung disease Postoperative ventilation Pulmonary function test 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of AnesthesiologyUniversity of ColoradoAuroraUSA
  2. 2.Department of SurgeryHokkaido UniversitySapporaJapan

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