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Acute Pancreatitis (AP)

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Imaging Acute Abdomen in Children

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Abstract

Acute and reversible inflammation of the pancreatic gland in children is rare but its incidence increases. More than 80% of children are reported to be older than 11-year. The most frequent etiologies are traumatic, idiopathic, biliary, congenital, secondary to multi-systemic diseases or drugs related. Up to 40% of children with AP have normal serum amylase and lipase levels. Mortality may be as high as 5%. Imaging (US, CT, MRI) allows the diagnosis of pancreatitis, searches for its causes, assesses complications and contributes to the follow-up. Normal imaging examinations, especially in the initial days of the disease, do not rule out the diagnosis of AP. The need for CT in children remains limited during AP since most of patients have a rapid favorable clinical outcome. In the near future, the use of contrast US and MR imaging with faster sequences will probably reduce even more the need for CT.

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References

  1. Nydegger A, Heine RG, Ranuh R, et al. Changing incidence of acute pancreatitis: 10-year experience at the Royal Children’s hospital, Melbourne. J Gastroenterol Hepatol. 2007;22:1313–6.

    Article  PubMed  Google Scholar 

  2. Bai HX, Lowe ME, Husain SZ. What have we learned about acute pancreatitis in children? J Pediatr Gastroenterol Nutr. 2011;52:262–70.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Lopez MJ. The changing incidence of acute pancreatitis in children: a single-institution perspective. J Pediatr. 2002;140:622–4.

    Article  PubMed  Google Scholar 

  4. Pant C, Deshpande A, Olyaee M, et al. Epidemiology of acute pancreatitis in hospitalized children in the United States from 2000–2009. PLoS One. 2014;9:e95552.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Benifla M, Weizman Z. Acute pancreatitis in childhood—analysis of literature data. J Clin Gastroenterol. 2003;37:169–72.

    Article  PubMed  Google Scholar 

  6. Meyer A, Coffey MJ, Oliver MR, et al. Contrasts and comparisons between childhood and adult onset acute pancreatitis. Pancreatology. 2013;13(4):429–35.

    Article  PubMed  Google Scholar 

  7. Marques VL, Gormezano NW, Bonfá E, et al. Pancreatitis subtypes survey in 852 childhood-onset systemic lupus erythematosus patients. J Pediatr Gastroenterol Nutr. 2016;62(2):328–34.

    Article  CAS  PubMed  Google Scholar 

  8. Kandula L, Lowe ME. Etiology and outcome of acute pancreatitis in infants and toddlers. J Pediatr. 2008;152(1):106–10.

    Article  PubMed  Google Scholar 

  9. Lautz TB, Chin AC, Radhakrishnan J. Acute pancreatitis in children: spectrum of disease and predictors of severity. J Pediatr Surg. 2011;46(6):1144–9.

    Article  PubMed  Google Scholar 

  10. Guo Q, Li M, Chen Y, Hu H, Hu W. Predictors for mortality following acute pancreatitis in children. Pediatr Surg Int. 2014;30(11):1111–5.

    Article  PubMed  Google Scholar 

  11. Eghtesad B, Reyes JD, Ashrafi M, et al. Pancreatitis after liver transplantation in children: a single-center experience. Transplantation. 2003;75(2):190–3.

    Article  PubMed  Google Scholar 

  12. Valentino M, Galloni SS, Rimondi MR, et al. Contrast-enhanced ultrasound in non-operative management of pancreatic injury in childhood. Pediatr Radiol. 2006;36(6):558–60.

    Article  PubMed  Google Scholar 

  13. Cai D, Parajuly SS, Wang H, et al. Accuracy of contrast-enhanced ultrasound compared with conventional ultrasound in acute pancreatitis: diagnosis and complication monitoring. Exp Ther Med. 2016;12(5):3189–94.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Mateen MA, Muheet KA, Mohan RJ, et al. Evaluation of ultrasound based acoustic radiation force impulse (ARFI) and eSie touch sonoelastography for diagnosis of inflammatory pancreatic diseases. JOP. 2012;13(1):36–44.

    Google Scholar 

  15. Darge K, Anupindi S. Pancreatitis and the role of US, MRCP and ERCP. Pediatr Radiol. 2009;39(Suppl 2):S153–7.

    Article  PubMed  Google Scholar 

  16. Almehdar A, Chavhan GB. MR cholangiopancreatography at 3.0 T in children: diagnostic quality and ability in assessment of common paediatric pancreatobiliary pathology. Br J Radiol. 2013;86(1025):20130036.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Chavhan GB, Babyn PS, Manson D, et al. Pediatric MR cholangiopancreatography: principles, technique, and clinical applications. Radiographics. 2008;28:1951–62.

    Article  PubMed  Google Scholar 

  18. Restrepo R, Hagerott HE, Kulkarni S, et al. Acute pancreatitis in pediatric patients: demographics, etiology, and diagnostic imaging. Am J Roentgenol. 2016;206(3):632–44.

    Article  Google Scholar 

  19. Anupindi SA, Chauvin NA, Khwaja A, et al. Magnetic resonance imaging of pancreaticobiliary diseases in children: from technique to practice. Pediatr Radiol. 2016;46(6):778–90.

    Article  PubMed  Google Scholar 

  20. Fabre A, Petit P, Gaudart J, et al. Severity scores in children with acute pancreatitis. J Pediatr Gastroenterol Nutr. 2012;55:266–7.

    Article  PubMed  Google Scholar 

  21. Chao HC, Lin SJ, Kong MS, et al. Sonographic evaluation of the pancreatic duct in normal children and children with pancreatitis. J Ultrasound Med. 2000;19:757–63.

    Article  CAS  PubMed  Google Scholar 

  22. Chapuy S, Gorincour G, Roquelaure B, et al. Sonographic diagnosis of a common pancreaticobiliary channel in children. Pediatr Radiol. 2006;36(12):1300–5.

    Article  PubMed  Google Scholar 

  23. Ohno Y, Kanematsu T. Annular pancreas causing localized recurrent pancreatitis in a child: report of a case. Surg Today. 2008;38(11):1052–5.

    Article  PubMed  Google Scholar 

  24. Lin YT, Chang MH, Hsu HY, Lai HS, Chen CC. A follow-up study of annular pancreas in infants and children (in Chinese). Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1998;39:89–93.

    CAS  PubMed  Google Scholar 

  25. Bolia R, Chong SY, Coleman L, MacGregor D, Hardikar W, Oliver MR. Autoimmune pancreatitis and IgG4 related disease in three children. ACG Case Rep J. 2016;3(4):e115.

    PubMed  PubMed Central  Google Scholar 

  26. Lautz TB, Turkel G, Radhakrishnan J, et al. Utility of the computed tomography severity index (Balthazar score) in children with acute pancreatitis. J Pediatr Surg. 2012;47:1185–91.

    Article  PubMed  Google Scholar 

  27. Thoeni RF. The revised Atlanta classification of acute pancreatitis: its importance for the radiologist and its effect on treatment. Radiology. 2012;262(3):751–64.

    Article  PubMed  Google Scholar 

  28. Banks PA, Freeman ML. Practice guidelines in acute pancreatitis. Am J Gastroenterol. 2006;101:2379–400.

    Article  PubMed  Google Scholar 

  29. Bolia R, Srivastava A, Yachha SK, et al. Prevalence, natural history, and outcome of acute fluid collection and pseudocyst in children with acute pancreatitis. J Pediatr Gastroenterol Nutr. 2015;61(4):451–5.

    Article  PubMed  Google Scholar 

  30. De Blaauw I, Winkelhorst JT, Rieu PN, et al. Pancreatic injury in children: good outcome of nonoperative treatment. J Pediatr Surg. 2008;43(9):1640–3.

    Article  PubMed  Google Scholar 

  31. Yoder SM, Rothenberg S, Tsao K, et al. Laparoscopic treatment of pancreatic pseudocysts in children. J Laparoendosc Adv Surg Tech A. 2009;19(Suppl 1):S37–40.

    Article  PubMed  Google Scholar 

  32. Larsen CC, Laursen CB, Dalby K, Graumann O. Splenic artery pseudoaneurysm due to acute pancreatitis in a 6-year-old boy with acute lymphoblastic leukaemia treated with L-aspariginase. BMJ Case Rep. 2014;20:1–3.

    Google Scholar 

  33. Puri A, Acharya H, Tyagi S, Curian S, et al. Pseudoaneurysm of the radial branch of the splenic artery with pancreatic pseudocyst in a child with recurrent acute pancreatitis: treatment with endovascular stent graft and cystogastrostomy. J Pediatr Surg. 2012;47(5):1012–5.

    Article  PubMed  Google Scholar 

  34. Hashimoto N, Yotani N, Michihata N, Tang J, Sakai H, Ishiguro A. Efficacy of pediatric acute pancreatitis scores at a Japanese tertiary center. Pediatr Int. 2016;58(3):224–8.

    Article  PubMed  Google Scholar 

  35. Balthazar EJ, Robinson DL, Megibow AJ, et al. Acute pancreatitis: value of CT in establishing prognosis. Radiology. 1990;174:331–6.

    Article  CAS  PubMed  Google Scholar 

  36. Mortele KJ, Ip IK, Wu BU, et al. Acute pancreatitis: imaging utilization practices in an urban teaching hospital--analysis of trends with assessment of independent predictors in correlation with patient outcomes. Radiology. 2011;258(1):174–8.

    Article  PubMed  Google Scholar 

  37. Alhajeri A, Erwin S. Acute pancreatitis: value and impact of CT severity index. Abdom Imaging. 2008;33(1):18–20.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatric Imaging, Hôpital Timone Enfants, 264 Rue St Pierre, 13385, Marseille Cedex 05, France

    Alexia Dabadie & Philippe Petit

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  1. Alexia Dabadie
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  2. Philippe Petit
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Correspondence to Philippe Petit .

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Editors and Affiliations

  1. Department of Pediatric Imaging, Jeanne de Flandre Hospital, Lille Cedex, France

    Fred E. Avni

  2. Department of Prenatal and Pediatric Imaging, Hospital Timone-Enfants, Marseille Cedex 05, France

    Philippe Petit

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Dabadie, A., Petit, P. (2018). Acute Pancreatitis (AP). In: E. Avni, F., Petit, P. (eds) Imaging Acute Abdomen in Children. Springer, Cham. https://doi.org/10.1007/978-3-319-63700-6_16

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  • DOI: https://doi.org/10.1007/978-3-319-63700-6_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-63699-3

  • Online ISBN: 978-3-319-63700-6

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