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Compartmental Theory in Uterine Cancer, Anatomical Considerations and Principles of Compartmental Cervical Cancer Surgery Step by Step

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Textbook of Gynecologic Robotic Surgery

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Abstract

Normal embryonic development forms a compartmental order of adult tissues with a high degree of compartmental control. In malignant progression embryologically active but in adults silenced programmes are reactivated but run in retrograde sequence. Thus, since reactivated morphogenetic programmes need topologically defined tissue domains—morphogenetic fields—to provide positional information for their interpretation, local tumour propagation is confined to permissive compartments. This leads to the concept of compartmental oncological surgery which will be outlined in principle and with respect to uterine cancer; the surgical procedure will be exemplified with respect to total mesometrial resection (TMMR) and therapeutic lymphadenectomy (tLNE) in cervical cancer.

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Author information

Authors and Affiliations

  1. Department of Gynaecology and Obstetrics, West German Cancer Center, University Hospital Essen, Essen, Germany

    Rainer Kimmig

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  1. Rainer Kimmig
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Correspondence to Rainer Kimmig .

Editor information

Editors and Affiliations

  1. Department of Gynaecological Oncology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, West Midlands, United Kingdom

    Alaa El-Ghobashy

  2. Department of Gynaecological Oncology, Royal Marsden and St George’s Hospitals, London, United Kingdom

    Thomas Ind

  3. Department of Obstetrics and Gynecology, Skane University Hospital, Lund, Sweden

    Jan Persson

  4. Department of Gynecological Oncology, Mayo Clinic, Phoenix, Arizona, USA

    Javier F. Magrina

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Kimmig, R. (2018). Compartmental Theory in Uterine Cancer, Anatomical Considerations and Principles of Compartmental Cervical Cancer Surgery Step by Step. In: El-Ghobashy, A., Ind, T., Persson, J., Magrina, J. (eds) Textbook of Gynecologic Robotic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-63429-6_14

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  • DOI: https://doi.org/10.1007/978-3-319-63429-6_14

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