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Nutrition in the Peri-HSCT Period

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Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist

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Abstract

Nutrition is an integral part of the supportive care of hematopoietic stem cell transplantation (HSCT) patients, and good nutritional status has been shown to improve outcomes in HSCT. However, providing proper nutritional support over the course of HSCT can prove to be challenging because many side effects associated with HSCT transplant negatively impact nutrition. This chapter details the factors that can lead to inadequate intake, poor GI absorption, and metabolic alterations. It also describes how the use of anthropometric assessments and energy need estimations play a key role in monitoring nutritional status and determining when further interventions are needed. Specific nutritional considerations in SOS/VOD and GvHD are discussed herein. Enteral and parenteral nutrition are compared: While enteral nutrition offers several advantages over total parenteral nutrition, there are situations in which full enteral nutrition is not feasible and parenteral nutrition is required to fulfill the patient’s caloric demands.

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Authors and Affiliations

  1. Division of Oncology, Children’s Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

    Arun Gurunathan MD & Jason L. Freedman MD, MSCE

  2. Department of Clinical Nutrition, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Judy Bailer RD, CSP, LDN, CNSC

Authors
  1. Arun Gurunathan MD
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  2. Judy Bailer RD, CSP, LDN, CNSC
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  3. Jason L. Freedman MD, MSCE
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Corresponding author

Correspondence to Jason L. Freedman MD, MSCE .

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Editors and Affiliations

  1. Division of Pediatric Oncology/Hematology, Penn State Health Children’s Hospital and Penn State Cancer Institute at the Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA

    Valerie I. Brown

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Gurunathan, A., Bailer, J., Freedman, J.L. (2018). Nutrition in the Peri-HSCT Period. In: Brown, V. (eds) Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist. Springer, Cham. https://doi.org/10.1007/978-3-319-63146-2_13

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  • DOI: https://doi.org/10.1007/978-3-319-63146-2_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-63144-8

  • Online ISBN: 978-3-319-63146-2

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