Radiopharmaceuticals for Therapy of Thyroid Diseases
Since the discovery of radium, the medical community has been interested in the application of unsealed radioactive isotopes to target and treat cancer and benign proliferative conditions. Radioactive iodine-131, as non radioactive Iodine, is taken up by thyroid cells, either normal or pathological, therefore thanks to its gamma and beta emissions, represents a radiopharmaceutical of choice for thyroid diseases. We give here a summary of the chemistry, mechanism of uptake and biodistribution of 131-Iodine with regard of its applications in thyroid benign and malignant diseases.The medical community has been interested in the application of unsealed radioactive isotopes to target and treat cancer and benign systemic and locoregional proliferative conditions. Lack of effective system agents coupled with the intention to use targeted therapy for treating cancer made radioisotopes an option for use in cancer.
- 2.Sodium Iodide I-131. https://www.drugs.com/pro/sodium-iodide-i-131.html.