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Stem Cells in Oncoplastic Breast Surgery

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Oncoplastic and Reconstructive Breast Surgery

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Abstract

There are many types of stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), and tissue-specific stem cells; however, clinical applications of ESCs and iPSCs are limited due to ethical consideration and cell regulation. Tissue-specific stem cells are also not really accessible and still in controversial for their therapeutic potential. These, hence, make MSCs of great interest to the field of stem cell therapy. This chapter establishes fundamental knowledge of MSCs, particularly adipose-derived stem cells (ADSCs), and extensive information of isolation methods and surface antigenic profiling of human ADSCs as well as their multilineage differentiation capacity for potential utility in cell-based therapy. These comprehensive contents with scientific supports will help surgeons to better understand the basis of ADSCs and their functions before implementation into clinical practices.

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Author information

Authors and Affiliations

  1. Research Group in Immunobiology and Therapeutic Sciences, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Premrutai Thitilertdecha

  2. Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Premrutai Thitilertdecha

  3. Faculty of Medicine, Department of Surgery, Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Visnu Lohsiriwat

Authors
  1. Premrutai Thitilertdecha
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  2. Visnu Lohsiriwat
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Editor information

Editors and Affiliations

  1. Our Lady of Grace Hospital, Positivo University, Curitiba, Brazil

    Cicero Urban

  2. Plastic and Reconstructive Division, European Institute of Oncology, Milan, Italy

    Mario Rietjens

  3. Memorial Sloan Kettering Cancer Center, New York, USA

    Mahmoud El-Tamer

  4. Memorial Sloan Kettering Cancer Center, New York, USA

    Virgilio S. Sacchini

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Thitilertdecha, P., Lohsiriwat, V. (2019). Stem Cells in Oncoplastic Breast Surgery. In: Urban, C., Rietjens, M., El-Tamer, M., Sacchini, V.S. (eds) Oncoplastic and Reconstructive Breast Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-62927-8_63

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  • DOI: https://doi.org/10.1007/978-3-319-62927-8_63

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-62925-4

  • Online ISBN: 978-3-319-62927-8

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