Skip to main content
SpringerLink
Log in

Multiple Myeloma and Plasmacytoma

  • Chapter
  • First Online:
Book cover Handbook of Evidence-Based Radiation Oncology

  • 2631 Accesses

Abstract

This chapter will discuss radiation therapy for multiple myeloma and solitary plasmacytoma.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References

  • Alexiou C, Kau RJ, Dietzfelbinger H, et al. Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts. Cancer. 1999;85:2305–14.

    Article  CAS  Google Scholar 

  • Catell D, Kogen Z, Donahue B, et al. Multiple myeloma of an extremity: must the entire bone be treated? Int J Radiat Oncol Biol Phys. 1998;40(1):117–9.

    Article  CAS  Google Scholar 

  • Creach CM, Foote RL, Netten-Wittich MA, et al. Radiotherapy for extramedullary plasmacytoma of the head and neck. Int J Radiat Oncol Biol Phys. 2009;73(3):789–94.

    Article  Google Scholar 

  • Durie BGM, Salmon SE. A clinical staging system for multiple myeloma. Cancer. 1975;36:842–54.

    Article  CAS  Google Scholar 

  • Frassica DA, Frassica FJ, Schray MF, et al. Solitary plasmacytoma of bone: Mayo Clinic experience. Int J Radiat Oncol Biol Phys. 1989 Jan;16(1):43–8.

    Article  CAS  Google Scholar 

  • Hirsch AE, Jha RM, et al. The use of vertebral augmentation and external beam radiation therapy in the multimodal management of malignant vertebral compression fractures. Pain Physician. 2011;14(5):447–58.

    PubMed  Google Scholar 

  • Hu K, Yahalom J. Radiotherapy in the management of plasma cell tumors. Oncology. 2000;14(1):100–11.

    Google Scholar 

  • Kim P, Hicks RJ, Wirth A, et al. Impact of (18)F-Fluorodeoxyglucose positron emission tomography before and after definitive radiation therapy in patients with apparently solitary plasmacytoma. Int J Radiat Oncol Biol Phys. 2008;74:740–6.

    Article  Google Scholar 

  • Kuiper R, van Duin M, van Vliet MH, Broijl A, van der Holt B, El Jarari L, van Beers EH, Mulligan G, Avet-Loiseau H, Gregory WM, Morgan G, Goldschmidt H, Lokhorst HM, Sonneveld P. Prediction of high- and low-risk multiple myeloma based on gene expression and the international staging system. Blood. 2015 Oct 22;126(17):1996–2004.

    Article  CAS  Google Scholar 

  • Kyle RA, Greipp PR. Smoldering multiple myeloma. N Engl J Med. 1980;302:1347.

    Article  CAS  Google Scholar 

  • Lee JW, Lee JE. Local radiotherapy for palliation in multiple myeloma patients with symptomatic bone lesions. Radiat Oncol J. 2016;34(1):59–63.

    Article  Google Scholar 

  • Moreau P, Facon T, Attal M, et al. Comparison fo 200mg/m2 mephalan and 8 Gy Tbi plus 140 mg/m2 mephalan as conditioning regiments for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma: Final analysis of the Intergroupe Francophone du Myelome 9502 randomized trial. Blood. 2002;99(3):731–5.

    Article  CAS  Google Scholar 

  • Myeloma Aredia Study Group. Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. N Engl J Med. 1996;334:488–93.

    Article  Google Scholar 

  • Nau K, Lewis W. Multiple myeloma: diagnosis and treatment. Am Fam Physician. 2008;78(7):853–9. 860

    PubMed  Google Scholar 

  • Ozsahin M, Tsang RW, Poortmans P, et al. Outcomes and patterns of failure in solitary plasmacytoma: a multicenter Rare Cancer Network study of 258 patients. Int J Radiat Oncol Biol Phys. 2006;64(1):210–7.

    Article  Google Scholar 

  • Palumbo A, Avet-Loiseau H, Oliva S, et al. Revised international staging system for multiple myeloma: a report from the IMWG. J Clin Oncol. 2015;33:2863–9.

    Article  CAS  Google Scholar 

  • Terpos E, et al. International Myeloma Working Group recommendations for the treatment of multiple myeloma related bone disease. J Clin Oncol. 2013;20(June):2347–57.

    Article  Google Scholar 

  • Rajkumar V, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15:e538–48.

    Article  Google Scholar 

  • Sasaki R, Yasuda K, Abe E, et al. Multi-institutional analysis of solitary extramedullary plasmacytoma of the head and neck treated with curative radiotherapy. Int J Radiat Oncol Biol Phys. 2012 Feb 1;82(2):626–34.

    Article  Google Scholar 

Download references

Acknowledgments

We thank Thomas T. Bui, MD; Kavita Mishra, MD, MPH; and Mack Roach III, MD, for their work on the prior edition of this chapter.

Author information

Authors and Affiliations

  1. Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA

    Lauren Boreta & Steve E. Braunstein

Authors
  1. Lauren Boreta
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Steve E. Braunstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Lauren Boreta .

Editor information

Editors and Affiliations

  1. The Oregon Clinic, Providence St. Vincent Medical Center, Portland, OR, USA

    Eric K. Hansen

  2. Department of Radiation Oncology, University of California, San Franc, SAN FRANCISCO, CA, USA

    Mack Roach III

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Boreta, L., Braunstein, S.E. (2018). Multiple Myeloma and Plasmacytoma. In: Hansen, E., Roach III, M. (eds) Handbook of Evidence-Based Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-62642-0_38

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-62642-0_38

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-62641-3

  • Online ISBN: 978-3-319-62642-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation