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Salivary Gland Tumors

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Handbook of Evidence-Based Radiation Oncology
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Abstract

This chapter will discuss the management of salivary gland tumors of the head and neck, with an emphasis on radiation therapy technique and published data.

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References

  • Al-Mamgani A, van Rooij P, Verduijn GM, et al. Long-term outcomes and quality of life of 186 patients with primary parotid carcinoma treated with surgery and radiotherapy at the Daniel den Hoed Cancer Center. Int J Radiat Oncol Biol Phys. 2012;84(1):189–95.

    Article  Google Scholar 

  • Armstrong JG, Harrison LB, Spiro RH, et al. Malignant tumors of major salivary gland origin. A matched-pair analysis of the role of combined surgery and postoperative radiotherapy. Arch Otolaryngol Head Neck Surg. 1990;116:290–3.

    Article  CAS  Google Scholar 

  • Armstrong JG, Harrison LB, Thaler HT, et al. The indications for elective treatment of the neck in cancer of the major salivary glands. Cancer. 1992;69:615–9.

    Article  CAS  Google Scholar 

  • Chen AM, Granchi PJ, Garcia J, et al. Local-regional recurrence after surgery without postoperative irradiation for carcinomas of the major salivary glands: implications for adjuvant therapy. Int J Radiat Oncol Biol Phys. 2007a;67:982–7.

    Article  Google Scholar 

  • Chen AM, Garcia J, Lee NY, Bucci MK, Eisele DW. Patters of nodal relapse after surgery and postoperative radiation therapy for carcinomas of the major and minor salivary glands: what is the role of elective neck irradiation? Int J Radiat Oncol Biol Phys. 2007b;67:988–94.

    Article  Google Scholar 

  • Garden AS, Weber RS, Ang KK, et al. Postoperative radiation therapy for malignant tumors of minor salivary glands. Cancer. 1994;73:2563–9.

    Article  CAS  Google Scholar 

  • Garden AS, Weber RS, Morrison WH, et al. The influence of positive margins and nerve invasion in adenoid cystic carcinoma of the head and neck treated with surgery and radiation. Int J Radiat Oncol Biol Phys. 1995;32:619–26.

    Article  CAS  Google Scholar 

  • Garden AS, El-Naggar AK, Morrison WH, et al. Postoperative radiotherapy for malignant tumors of the parotid gland. Int J Radiat Oncol Biol Phys. 1997;37:79–85.

    Article  CAS  Google Scholar 

  • Hsieh CE, Lin CY, Lee LY, et al. Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but not overall survival in patients with salivary gland adenoid cystic carcinoma—a propensity score matched study. Radiat Oncol. 2016;11(47):1–10.

    Google Scholar 

  • Jensen AD, Nikoghosyan AV, Lossner K, et al. COSMIC: a regimen of intensity modulated radiation therapy plus dose-escalated, raster-scanned carbon ion boost for malignant salivary gland tumors: results of the prospective phase 2 trial. Int J Radiat Oncol Biol Phys. 2015;93(1):37–46.

    Article  Google Scholar 

  • Laramore GE, Krall JM, Griffin TW, et al. Neutron versus photon irradiation for unresectable salivary gland tumors: final report of an RTOG-MRC randomized clinical trial. Radiation Therapy Oncology Group. Medical Research Council. Int J Radiat Oncol Biol Phys. 1993;27:235–40.

    Article  CAS  Google Scholar 

  • Loh KS, Barker E, Bruch G, et al. Prognostic factors in malignancy of the minor salivary glands. Head Neck. 2009;31:58–63.

    Article  Google Scholar 

  • Mendenhall WM, Morris CG, Amdur RJ, et al. Radiotherapy alone or combined with surgery for adenoid cystic carcinoma of the head and neck. Head Neck. 2004;26:154–62.

    Article  Google Scholar 

  • Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg. 1986;68(3):177–84.

    Article  Google Scholar 

  • Tanvetyanon T, Qin D, Padhya T, et al. Outcomes of postoperative concurrent chemoradiotherapy for locally advanced major salivary gland carcinoma. Arch Otolaryngol Head Neck Surg. 2009;35(7):687–92.

    Article  Google Scholar 

  • Terhaard CH, Lubsen H, Rasch CR, et al. The role of radiotherapy in the treatment of malignant salivary gland tumors. Int J Radiat Oncol Biol Phys. 2005;61:103–11.

    Article  Google Scholar 

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Acknowledgment

We thank Chien Peter Chen MD and Naomi R. Schechter MD for their work on the prior edition of this chapter.

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Correspondence to Christopher H. Chapman .

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Chapman, C.H., Garsa, A. (2018). Salivary Gland Tumors. In: Hansen, E., Roach III, M. (eds) Handbook of Evidence-Based Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-62642-0_10

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  • DOI: https://doi.org/10.1007/978-3-319-62642-0_10

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-62642-0

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