Cystic lesions originate from embryonic vestiges remaining as a consequence of the incomplete obliteration of the urachus and omphalomesenteric duct. They are more often single than multiple and are usually isolated, even though with association with other congenital anomalies, usually of the gastrointestinal tract, and other syndromes. The presence of multiple umbilical cord cysts is associated with an increased risk of miscarriage, aneuploidy and congenital anomalies. Additionally, pseudocysts have also been described, originating as a result of myxoid degeneration of the Wharton’s jelly secondary to persistent patent urachus, urachal cysts or abdominal wall defects.
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