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Physiology, Ultrastructure, Ultrasonography and Pharmacology of the Umbilical Cord

  • Mohamed Fahmy
Chapter

Abstract

The complexity of umbilical cord built has long been of interest to anatomists. A look at all mammals shows a variety of design adaptations. In humans, it has been determined that there are several designs.What these differences mean to the fetusis unknown.Attempts by several scientists to understand how the umbilical cord works have taught us thatthe cord is more like an organ rather than a rigid conduit (pipeline). Not all cords are alike. Just as there are different kinds of hair (curly/straight, thick/thin), there are different kinds of cords.

Keywords

Wharton’s jelly Cord design Velamentous insertions Bifurcated Cord design Spiral turns Helical configuration and single umbilical artery 

References

  1. 1.
    Di Naro E, Raio L, Ghezzi F, Franchi M, Romano F, D’Addario V. Longitudinal umbilical vein blood flow changes in normal and growth-retarded fetuses. Acta Obstet Gynecol Scand. 2002;81(6):527–33.CrossRefGoogle Scholar
  2. 2.
    Benoit R, Copel J, Williams K. Does single umbilical artery (SUA) predict IUGR? Am J Obstet Gynecol. 2002;187:208. (abstract 546)Google Scholar
  3. 3.
    Dudiak CM, Salomon CG, Posniak HV, Olson MC, Flisak ME. Sonography of the umbilical cord. Radiographics. 1995;15:1035–50.CrossRefGoogle Scholar
  4. 4.
    Strong TH, Jarles DL, Vega JS, Feldman DB. The umbilical coiling index. Am J Obstet Gynecol. 1994;170:29–32.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Spatz WB. Nabelschnur-Längen bei Insektivoren und Primaten. Z Säugetierkd. 1968;33:226–39.Google Scholar
  6. 6.
    Blackburn W, Cooley NR, Manci EA. Correlations between umbilical cord structure-composition and normal and abnormal fetal development. In: Saul RA, editor. Proceedings of the greenwood genetics conference, vol. 7. Clinton: Jacobs Press; 1988. p. 180–1.Google Scholar
  7. 7.
    Fletcher S. Chirality in the umbilical cord. Br J Obstet Gynaecol. 1993;100:234–6.CrossRefPubMedGoogle Scholar
  8. 8.
    Shepherd JT. Bayliss response in the umbilical artery. Fed Proc. 1968;27:1408–9.PubMedGoogle Scholar
  9. 9.
    Röckelein G, Scharl A. Scanning electron microscopic investigations of the human umbilical artery intima: a new conception on postnatal arterial closure mechanism. Virchows Arch A. 1988;413:555–61.CrossRefGoogle Scholar
  10. 10.
    LeDonne AT, McGowan L. Effect of an oxytocic on umbilical cord venous pressure. Obstet Gynecol. 1967;30:103–7.PubMedGoogle Scholar
  11. 11.
    McCoshen JA, Tulloch HV, Johnson KA. Umbilical cord is the major source of prostaglandin E2 in the gestational sac during term labor. Am. J. Obstet. Gynecol. 1989;160:973–8.CrossRefPubMedGoogle Scholar
  12. 12.
    Salas SP, Power RF, Singleton A, Wharton J, Polak JM, Brown J. Heterogeneous binding sites for a-atrial natriuretic peptide in human umbilical cord and placenta. Am J Physiol. 1991;261:R633–8.PubMedGoogle Scholar
  13. 13.
    Cai WQ, Bodin P, Sexton A, Loesch A, Burnstock G. Localization of neuropeptide Y and atrial natriuretic peptide in the endothelial cells of human umbilical blood vessels. Cell Tissue Res. 1993;272:175–81.CrossRefPubMedGoogle Scholar
  14. 14.
    Okatani Y, Taniguchi K, Sagara Y. Amplifying effect of endothelin-1 on serotonin-induced vasoconstriction of human umbilical artery. Am J Obstet Gynecol. 1995;172:1240–5.CrossRefPubMedGoogle Scholar
  15. 15.
    De Sa MF, Meirelles RS. Vasodilating effect of estrogen on the human umbilical artery. Gynecol Investig. 1977;8:307–13.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Mohamed Fahmy
    • 1
  1. 1.Pediatric SurgeryAl Azher University Pediatric SurgeryCairoEgypt

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