Combining Refinement and Signal-Temporal Logic for Biological Systems

Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 10383)


System-level modeling and analysis of biological phenomena have become an important research topic amongst different fields including mathematics, computer science, electrical and system engineering. This is a consequence of the recent development in these fields which can be utilized to understand the dynamics of complex biological organisms such as cancer, malaria and diabetes, etc. However, the concept of model refinement (i.e., the transformation of an abstract models into a detailed model) is largely unexplored in biology. In this paper, we describe our ongoing project which aims at combining the concept of model refinement and temporal logic for the analysis of a wide class of biological systems.


Biomodeling Refinement Event-B Signal-Temporal Logic 


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Computational Biomodeling Laboratory, Department of Computer ScienceÅbo Akademi University, Turku Centre for Computer ScienceTurkuFinland
  2. 2.Department of Computing and SoftwareMcMaster UniversityHamiltonCanada

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