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Pharmacology of Opioids

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Basic Sciences in Anesthesia

Abstract

Opioids are the most prevalently used analgesic perioperatively and in patients with chronic pain syndromes.. The analgesic effects of opioids are influenced by their route of administration, pharmacokinetics/pharmacodynamics, receptor downstream signaling, and non-opioid signal modifying mechanisms. Although opioids are effective analgesic drugs, their use is also associated with adverse events.

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Authors and Affiliations

  1. Department of Anesthesiology and Perioperative Medicine, The University of Texas – MD Anderson Cancer Center, Anesthesiology and Surgical Oncology Research Group, Houston, TX, USA

    Juan P. Cata

  2. Department of Anesthesiology and Perioperative Medicine, Division of Anesthesiology and Critical Care, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Shreyas P. Bhavsar

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Correspondence to Juan P. Cata .

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Editors and Affiliations

  1. Departments of General Anesthesia and Outcomes Research, Anesthesiology Institute, Cleveland Clinic Lerner College of Medicine, Case Western University, Cleveland, OH, USA

    Ehab Farag

  2. Center for Anesthesiology Education, Anesthesiology Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA

    Maged Argalious

  3. Department of General Anesthesia, Anesthesiology Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA

    John E. Tetzlaff

  4. Department of Anesthesiology & Pain Medicine, University of Washington, Seattle, WA, USA

    Deepak Sharma

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Cata, J.P., Bhavsar, S.P. (2018). Pharmacology of Opioids. In: Farag, E., Argalious, M., Tetzlaff, J.E., Sharma, D. (eds) Basic Sciences in Anesthesia. Springer, Cham. https://doi.org/10.1007/978-3-319-62067-1_7

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