Pre- and Probiotics and Immunostimulants in Siberian Sturgeon: Gut Microbiota and Immunomodulation

  • Zahra GeraylouEmail author


The endogenous gut microbiota serves a variety of functions in the host. They protect the host against pathogen invasion to the gastrointestinal tract, in mediating the development, maintenance and effective functionality of the intestinal mucosa and gut-associated lymphoid tissue. Gut microbiota is capable and able to support host digestive function via the production of wide range of exogenous digestive enzymes and vitamins. Therefore, manipulation of the gut microbiota through dietary supplementation of beneficial microbe (probiotics), and non-digestible substances (prebiotics) that selectively stimulate the growth of one or limited health-promoting bacteria in the intestine of the host, not only provides benefit to the host from nutritional point of view but also as an alternate viable therapeutic modality to overcome the adverse effects of antibiotics and drugs.

The use of immunostimulants for the prevention of fish disease has become more promising over the last decades. Immunostimulants enhance the innate defence mechanisms and increase resistance to specific pathogens by conferring the signals to the animal’s neuro-immune-endocrine system or various cell signalling pathways.

The effects of pre- and probiotics or their combination, synbiotic, and immunostimulants on Siberian sturgeon growth performance, intestinal microbiota modulation, innate immune response and health have been discussed in this chapter.


Prebiotic Probiotic Symbiotic Immunostimulants Gut microbiota Immune response Siberian sturgeon 


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Laboratory of MicrobiologyFaculty of ScienceUGentBelgium

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