Abstract
Small cell tumours constitute a heterogeneous group of tumours that are difficult to distinguish from each other and for which there is no strict classification. In the setting of a tumour with a small cell phenotype in the thyroid, the first approach is to separate lymphomas from the other small cell tumours with the help of routine immunohistochemistry; afterwards, if the small cell tumour is not a lymphoma, one has to try to separate a primary from a metastatic neoplasm. The distinction between primary and metastatic tumours may require a solid collaboration with the clinical team, a broad panel of immunohistochemical and, sometimes, molecular tests, and often the second opinion of an experienced pathologist.
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Eloy, C. et al. (2018). Small Cell Tumours. In: Cameselle-Teijeiro, J., Eloy, C., Sobrinho-Simões, M. (eds) Rare Tumors of the Thyroid Gland. Springer, Cham. https://doi.org/10.1007/978-3-319-61182-2_4
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DOI: https://doi.org/10.1007/978-3-319-61182-2_4
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