Advertisement

Miscellaneous Epithelial and Epithelial-like Tumors

  • Roque Gabriel Wiseman PintoEmail author
  • Živa Pohar-Marinšek
Chapter

Abstract

This chapter presents various epithelial and epithelial-like lesions which are rare in children. They have the same morphology and immunohistochemical profiles as the same tumors when seen in adults. However, the frequency of presentation of these lesions in specific locations, as well as their differential diagnoses, may be different. Due to their infrequency and sometimes morphologic similarity to more common round cell tumors, they are not always considered as differential diagnostic possibilities. Thyroid lesions will be considered in a separate chapter due to their importance in childhood pathology.

Keywords

Epithelial tumors Undifferentiated carcinoma of nasopharyngeal type Pilomatricoma Salivary gland tumors Melanoma Germ cell tumors Teratoma Seminoma Dysgerminoma Yolk-sac tumor Embryonal carcinoma Choriocarcinoma 

References

  1. 1.
    Lu S, Chang H, Sun X, Zhen Z, Sun F, Zhu J, et al. Long-term outcomes of nasopharyngeal carcinoma in 148 children and adolescents. Medicine (Baltimore). 2016;95:e3445.CrossRefGoogle Scholar
  2. 2.
    Viguer JM, Jiménez-Heffernan JA, López-Ferrer P, Banaclocha M, Vicandi B. Fine-needle aspiration cytology of metastatic nasopharyngeal carcinoma. Diagn Cytopathol. 2005;32:233–7.CrossRefPubMedGoogle Scholar
  3. 3.
    Mohanty SK, Dey P, Ghoshas S, Saikia UN. Cytologic features of metastatic nasopharyngeal carcinoma. Diagn Cytopathol. 2002;27:340–2.CrossRefPubMedGoogle Scholar
  4. 4.
    Lee WY, Hsiao JR, Jin YT, Tsai ST. Epstein-Barr virus detection in neck metastases by in-situ hybridization in fine-needle aspiration cytologic studies: an aid for differentiating the primary site. Head Neck. 2000;22:336–40.CrossRefPubMedGoogle Scholar
  5. 5.
    Barroca H. Pediatric cytology (Up to date 2016). Nasopharyngeal carcinoma. 2016. www.eurocytology.eu/en/course/1685. Accessed 12 Apr 2017.
  6. 6.
    Roche NA, Monstrey SJ, Matton GE. Pilomatricoma in children: common but often misdiagnosed. Acta Chir Belg. 2010;110:250–4.CrossRefPubMedGoogle Scholar
  7. 7.
    Wang J, Cobb CJ, Martin SE, Venegas R, Wu N, Greaves TS. Pilomatrixoma: clinicopathologic study of 51 cases with emphasis on cytologic features. Diagn Cytopathol. 2002;27:167–72.CrossRefPubMedGoogle Scholar
  8. 8.
    Dubb M, Michelow P. Fine needle aspiration cytology of pilomatrixoma and differential diagnoses. Acta Cytol. 2009;53:683–8.PubMedGoogle Scholar
  9. 9.
    Rebours C, Couloigner V, Galmiche L, Casiraghi O, Badoual C, Boudjemaa S, et al. Pediatric salivary gland carcinomas: diagnostic and therapeutic management. Laryngoscope. 2017;127:140–7.CrossRefPubMedGoogle Scholar
  10. 10.
    Göret CC, Göret NE, Özdemir ZT, Özkan EA, Doğan M, Yanık S, et al. Diagnostic value of fine needle aspiration biopsy in non-thyroidal head and neck lesions: a retrospective study of 866 aspiration materials. Int J Clin Exp Pathol. 2015;8:8709–16.PubMedPubMedCentralGoogle Scholar
  11. 11.
    Klijanienko J, Vielh P. Salivary gland tumours. In: Orell SR, editor. Monographs in clinical cytology, vol. 15. Basel: Karger; 2000.Google Scholar
  12. 12.
    Pauniaho SL, Salonen J, Helminen HO, Vettenranta K, Heikinheimo M. Germ cell tumours in children and adolescents in Finland: trends over 1969–2008. Cancer Causes Control. 2014;25:1337–41.CrossRefPubMedGoogle Scholar
  13. 13.
    Woodward PJ, Heidenreich A, Looijenga LHJ, Oosterhuis JW, McLeod DG, Møller H, et al. Germ cell tumors. In: Eble JN, Sauter G, Epstein JI, Sesterhenn IA, editors. Pathology and genetics of tumours of the urinary system and male genital organs. Lyon: IARC Press; 2004. p. 221–49.Google Scholar
  14. 14.
    Gupta R, Mathur SR, Arora VK, Sharma SG. Cytologic features of extragonadal germ cell tumors: a study of 88 cases with aspiration cytology. Cancer. 2008;25(114):504–11.CrossRefGoogle Scholar
  15. 15.
    Stanley MW, Powers CN, Pitman MB, Korourian S, Bardales RH, Khurana K. Cytology of germ cell tumours. Extragonadal, extracranial and intraoperative problems. Cancer. 1997;81:220–7.CrossRefPubMedGoogle Scholar
  16. 16.
    Herman SJ, Hobub RV, Weisbrod GL, Chamberlain DW. Anterior mediastinal masses: utility of trandthoracic needle biopsy. Radiology. 1991;180:167–70.CrossRefPubMedGoogle Scholar
  17. 17.
    Baslev E, Francis D, Jacobsen GK. Testicular germ cell tumours: classification based on fine needle aspiration biopsy. Acta Cytol. 1990;34:690–4.Google Scholar
  18. 18.
    Mehregan AH, Mehregan DA. Malignant melanoma in childhood. Cancer. 1993;71:4096–103.CrossRefPubMedGoogle Scholar
  19. 19.
    Barnhill RL. Childhood melanoma. In: LeBoit PE, Burg G, Weedon D, Sarasin A, editors. WHO classification of tumours. Pathology and genetics of skin tumours. Lyon: IARC Press; 2006.Google Scholar
  20. 20.
    Zadnik V, Primic Zakelj M, Lokar K, Jarm K, Ivanus U, Zagar T. Cancer burden in Slovenia with the time trends analysis. Radiol Oncol. 2017;51(1):47–55.CrossRefPubMedPubMedCentralGoogle Scholar
  21. 21.
    Prieto-Granada CN, Lezcano C, Scolyer RA, Mihm MC Jr, Piris A. Lethal melanoma in children: a clinicopathological study of 12 cases. Pathology. 2016;48:705–11.CrossRefPubMedGoogle Scholar
  22. 22.
    Voit CA, van Akkooi AC, Eggermont AM, Schäfer-Hesterberg G, Kron M, Ulrich J, et al. Fine needle aspiration cytology of palpable and nonpalpable lymph nodes to detect metastatic melanoma. J Natl Cancer Inst. 2011;103:1771–7.CrossRefPubMedGoogle Scholar
  23. 23.
    Wilkerson AE, Glasgow MA, Hiatt KM. Immunoreactivity of CD99 in invasive malignant melanoma. J Cutan Pathol. 2006;33:663–6.CrossRefPubMedGoogle Scholar
  24. 24.
    Kim JY, Choi JE, Ahn HH, Kye YC, Seo SH. A case of spitzoid melanoma with lymph node metastasis in a child. J Korean Med Sci. 2012;27:454–7.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Roque Gabriel Wiseman Pinto
    • 1
    Email author
  • Živa Pohar-Marinšek
    • 2
  1. 1.Department of PathologyGoa Medical CollegeBambolimIndia
  2. 2.Department of CytopathologyInstitute of OncologyLjubljanaSlovenia

Personalised recommendations