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Cancer of the Gallbladder and Biliary Tree

  • Marco Filauro
  • Giulio Angelini
  • Federico Fazio
  • Andrea Barberis
Chapter

Abstract

Cholangiocarcinoma and gallbladder carcinoma are uncommon and aggressive cancers of the biliary system; its incidence is rising worldwide, and it has a poor prognosis given that the diagnosis is often delayed due to subtle symptoms. Radical surgical resection is the only possible curative treatment, but only few patients are resectable at the time of the diagnosis. Surgical procedures are different according to tumor location and, in some cases, need highly demolitive interventions. Alternative palliative procedures are available as well as systematic chemo- and radiotherapy that need to be organized within a multidisciplinary team, ideally in a high-volume center. In this chapter, we illustrate the various aspects in which this disease presents and possible therapeutic and palliative options, with an eye to the elderly population that almost exclusively characterizes patients with which we deal every day in our clinical practice. Although until a few years ago old age was considered a contraindication to surgery, ever more studies are showing how age per se is not a contraindication to surgery.

Keywords

Gallbladder cancer Biliary tree cancer Cholangiocarcinoma Intrahepatic Perihilar Obstructive jaundice Liver surgery Pancreaticoduodenectomy 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Marco Filauro
    • 1
  • Giulio Angelini
    • 1
  • Federico Fazio
    • 1
  • Andrea Barberis
    • 1
  1. 1.E.O. Ospedali GallieraGenovaItaly

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