Advertisement

PET/CT in Gall Bladder and Biliary Tract Malignancies

  • Archi AgrawalEmail author
  • Nilendu Purandare
  • Sneha Shah
  • Ameya Puranik
  • Venkatesh Rangarajan
Chapter
  • 593 Downloads
Part of the Clinicians’ Guides to Radionuclide Hybrid Imaging book series (CGRHI)

Abstract

In this chapter we shall discuss the role of positron emission tomography (PET/CT) in biliary tract malignancies—i.e., gall bladder cancer (GBC) and cholangiocarcinoma (CCA). Though carcinoma of ampulla of Vater could also be included here, it will be discussed separately in pancreatic malignancies.

Keywords

Biliary Tract Malignancy Gallbladder Cancer SUV Max Bile Duct Cancer Lymph Nodal Metastases 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Levy AD, Murakata LA, Rohrmann CA Jr. Gallbladder carcinoma: radiologic-pathologic correlation. Radiographics 2001, 21:295–314.Google Scholar
  2. 2.
    Rodríguez-Fernández A, Gómez-Río M, Medina-Benítez A, Moral JV, Ramos-Font C, Ramia-Angel JM, Llamas-Elvira JM, Ferrón-Orihuela JA, Lardelli-Claret P. Application of modern imaging methods in diagnosis of gallbladder cancer. J Surg Oncol. 2006;93:650–64.CrossRefPubMedGoogle Scholar
  3. 3.
    Duffy A, Capanu M, Abou-Alfa GK, Huitzil D, Jarnagin W, Fong Y, D’Angelica M, Dematteo RP, Blumgart LH, O’Reilly EM. Gallbladder cancer (GBC):10-year experience at Memorial Sloan-Kettering Cancer Centre (MSKCC). J Surg Oncol. 2008;98:485–9.Google Scholar
  4. 4.
    Agrawal A, Rangarajan V. Appropriateness criteria of FDG PET/CT in oncology. Indian J Radiol Imaging. 2015;25(2):88–101.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Ramos-Font C, Ramos-Font C, Gómez-Rio M, Rodríguez-Fernández A, et al. Ability of FDG-PET/CT in the detection of gallbladder cancer. J Surg Oncol. 2014;109(3):218–24.CrossRefPubMedGoogle Scholar
  6. 6.
    Leung U, Pandit-Taskar N, Corvera CU, et al. Impact of pre-operative positron emission tomography in gallbladder cancer. HPB (Oxford). 2014;16:1023–30.CrossRefGoogle Scholar
  7. 7.
    Goel M, Tamhankar A, Rangarajan V, Patkar S, Ramadwar M, Shrikhande SV. Role of PET CT scan in redefining treatment of incidental gall bladder carcinoma. J Surg Oncol. 2016;113(6):652–8.CrossRefPubMedGoogle Scholar
  8. 8.
    Annunziata S, Pizzuto DA, Caldarella C, Galiandro F, Sadeghi R, Treglia G. Diagnostic accuracy of fluorine-18-fluorodeoxyglucose positron emission tomography in gallbladder cancer: a meta-analysis. World J Gastroenterol. 2015;21(40):11481–8.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Hwang JP, Lim I, Na II, et al. Prognostic value of maxSUV measured by fluorine-18 fluorodeoxyglucose positron emission tomography with computed tomography in patients with gallbladder cancer. Nucl Med Mol Imaging. 2014;48(2):114–20.Google Scholar
  10. 10.
    Yoo J, Choi JY, Lee KT, et al. Prognostic significance of volume-based metabolic parameters by (18)FFDG PET/CT in gallbladder carcinoma. Nucl Med Mol Imaging. 2012;46(3):201–6.CrossRefPubMedCentralGoogle Scholar
  11. 11.
    Redondo F, Butte J, Lavados H, et al. 18F-FDG PET/CT performance and prognostic value in patients with incidental gallbladder carcinoma. J Nucl Med. 2012;53(515):515.Google Scholar
  12. 12.
    Blechacz BR, Gores GJ. Cholangiocarcinoma. Clin Liver Dis. 2008;12:131e50.CrossRefGoogle Scholar
  13. 13.
    De Groen PC, Gores GJ, LaRusso NF, Gunderson LL, Nagorney DM. Biliary tract cancers. N Engl J Med. 1999;341:1368e78.CrossRefGoogle Scholar
  14. 14.
    Gores GJ. Early detection and treatment of cholangiocarcinoma. Liver Transpl. 2000;6:S30e4.CrossRefGoogle Scholar
  15. 15.
    Zech CJ, Shoenberg SO, Reiser M, Helmberger T. Cross-sectional imaging of biliary tumors: current clinical status and future developments. Eur Radiol. 2004;14:1174e87.CrossRefGoogle Scholar
  16. 16.
    Kim JY, Kim MH, Lee TY, et al. Clinical role of 18F-FDG PET-CT in suspected and potentially operable cholangiocarcinoma: a prospective study compared with conventional imaging. Am J Gastroenterol. 2008;103:1145–51.CrossRefPubMedGoogle Scholar
  17. 17.
    Petrowsky H, Wildbrett P, Husarik DB, et al. Impact of integrated positron emission tomography and computed tomography on staging and management of gallbladder cancer and cholangiocarcinoma. J Hepatol. 2006;45:43–50.CrossRefGoogle Scholar
  18. 18.
    Moon CM, Bang S, Chung JB, Park SW, Song SY, Yun M, et al. Usefulness of 18F- fluorodeoxyglucose positron emission tomography in differential diagnosis and staging of cholangiocarcinomas. J Gastroenterol Hepatol. 2008;23:759e65.CrossRefGoogle Scholar
  19. 19.
    Corvera CU, Blumgart LH, Akhurst T, DeMatteo RP, D’Angelica M, Fong Y, et al. 18F-fluorodeoxyglucose positron emission tomography influences management decisions in patients with biliary cancer. J Am Coll Surg. 2008;206:57e65.CrossRefGoogle Scholar
  20. 20.
    Keiding S, Hansen SB, Rasmussen HH, Gee A, Kruse A, Roelsgaard K, et al. Detection of cholangiocarcinoma in primary sclerosing cholangitis by positron emission tomography. Hepatology. 1998;28:700e6.Google Scholar
  21. 21.
    Anderson CD, Rice MH, Pinson CW, Chapman WC, Chari RS, Delbeke D. Fluorodeoxyglucose PET imaging in the evaluation of gallbladder carcinoma and cholangiocarcinoma. J Gastrointest Surg. 2004;8:90–7.CrossRefGoogle Scholar
  22. 22.
    Kluge R, Schmidt F, Caca K, Barthel H, Hesse S, Georgi P, et al. Positron emission tomography with [18F]fluoro-2-deoxy-D-glucose for diagnosis and staging of bile duct cancer. Hepatology. 2001;33:1029e35.CrossRefGoogle Scholar
  23. 23.
    Nakeeb A, Pitt HA, Sohn TA, et al. Cholangiocarcinoma: a spectrum of intrahepatic, perihilar, and distal tumors. Ann Surg. 1996;224:463–473, discussion 473–475.CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Jadvar H, Henderson RW, Conti PS. [F-18]Fluorodeoxyglucose positron emission tomography and positron emission tomography: computed tomography in recurrent and metastatic cholangiocarcinoma. J Comput Assist Tomogr. 2007;31:223–8.CrossRefPubMedGoogle Scholar
  25. 25.
    Kato T, Tsukamoto E, Kuge Y, Katoh C, Nambu T, Nobuta A, et al. Clinical role of [18]F-FDG PET for initial staging of patients with extrahepatic bile duct cancer. Eur J Nucl Med. 2002;29:1047e54.Google Scholar
  26. 26.
    Seo S, Hatano E, Higashi T, Nakajima A, Nakamoto Y, Tada M, et al. Fluorine-18 fluorodeoxyglucose positron emission tomography predicts lymph node metastasis, P-glycoprotein expression, and recurrence after resection in mass forming intrahepatic cholangiocarcinoma. Surgery. 2008;143:769e77.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Archi Agrawal
    • 1
    Email author
  • Nilendu Purandare
    • 1
  • Sneha Shah
    • 1
  • Ameya Puranik
    • 1
  • Venkatesh Rangarajan
    • 1
  1. 1.Tata Memorial HospitalMumbaiIndia

Personalised recommendations