Abstract
The silicon electro-photonic platform was introduced in Chap. 4, while its capabilities for monitoring electrochemical reactions in situ and site-selective functionalisation were presented in Chap. 5. By tailoring the light-matter interaction, it is also possible to create a sensor with the potential to enable detailed quantification of biological and molecular layers.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
X. Fan, Y. Sun, Optical ring resonators for biochemical and chemical sensing. Anal. Bioanal. Chem. 399, 205–211 (2011)
J. Homola, S. Yee, G. Gauglitz, Surface plasmon resonance sensors: review. Sens. Actuators 54(54), 3–15 (1999)
Yuanjin Zhao, Gu Xiangwei Zhao, Zhongze, Photonic crystals in bioassays. Adv. Funct. Mater. 20(18), 2970–2988 (2010)
R.G. Heideman, P.V. Lambeck, Remote opto-chemical sensing with extreme sensitivity: design, fabrication and performance of a pigtailed integrated optical phase-modulated machzehnder interferometer system. Sens. Actuators B Chem. 61 (13),100–127 (1999), http://www.sciencedirect.com/science/article/pii/S092540059900283X
S.E. Radford, Protein folding: progress made and promises ahead. Trends Biochem. Sci. 25(12), 611–618 (2000)
N. J. Freeman, G. H. Cross, M. J. Swann. Dual Polarization Interferometry: A Real-Time Optical Technique for Measuring (Bio)molecular Orientation, Structure and Function at the Solid/Liquid Interface. Wiley (2008)
S. Werquin, J.W. Hoste, P. Bienstman, Conformational analysis of proteins with a dual polarisation silicon microring. Opt. Express 22(3), 2807–2820 (2014)
A. N. Parikha, D. L. Allarac, Handbook of Biofunctional Surfaces. Pan Stanford Publishing (2013)
K. Okamoto, Fundamentals of Optical Waveguides. Elsevier (2006)
W. Bogaerts, P. De Heyn, T. Van Vaerenbergh, K. De Vos, S. Kumar, Silicon microring resonators. Laser Photonics Rev. 6(1), 47–73 (2012)
K. De Vos, Label-free silicon photonics biosensor platform with microring resonators. PhD thesis, University of Ghent (2010)
S. Johnson, D. Evans, S. Laurenson, D. Paul, A.G. Davies, P. Ko Ferrigno, C. Wlti, Surface-immobilized peptide aptamers as probe molecules for protein detection. Anal. Chem. 80, 978–983 (2008)
S.H. Brorson, Bovine serum albumin (BSA) as a reagent against non-specific immunogold labeling on lrwhite and epoxy resin. Micron 28, 189–195 (1997)
D.C. Carter, J.X. Ho, Structure of serum albumin. Adv. Protein Chem. 45, 153–203 (1994)
M.J. Swann, G.H. Cross, A. Reeves, S. Brand, N.J. Freeman, L.L. Peel, J.R. Lu, Real time, high resolution studies of protein adsorption and structure at the solidliquid interface using dual polarization interferometry. J. Phys. Condens. Matter 16(26), S2493 (2004)
J-W. Hoste, Dual Polarization Ring Resonator for Conformational Analysis of Molecular-sized Layers. PhD thesis, Universiteit Gent (2015)
Vincent S. Stoll, John S. Blanchard. [4] buffers: Principles and practice. In: Murray P. Deutscher (ed.), Guide to Protein Purification, vol. 182 of Methods in Enzymology, pp. 24–38. Academic Press (1990)
A. Ulman, Formation and structure of self-assembled monolayers. Chem. Rev. 96, 1533–1554 (1996)
R. Woodman, M. Crawford, P. K. Ferrigno, Peptide aptamers: Tools for biology and drug discovery. 2(1), 72–79 (2003)
X. Luo, J. Davis, Electrical biosensors and the label free detection of protein disease biomarkers. Chem. Soc. Rev., 5944–5962 (2013)
D. Chandler, Interfaces and the driving force of hydrophobic assembly. Nature 437, 640–647 (2005)
R.G. Berendsen, H.G.J.M. Janssen, T.J.J. Binnendijk, C.W. Hilbers, G.A. van der Marel, C.A.G. Haasnoot, kinetics and thermodynamics of dna hairpin fragments in solution. J. Biomol. Struct. Dyn. 1(1), 115–129 (1983)
J. Bath, A. Tyrrell, M. Costa, A clocked finite state machine built from DNA. Chem. Commun. 49, 237–239 (2013)
R. Sha, Omabegho, To. N. C. Seeman. A bipedal dna brownian motor with coordinated legs. Science 324(5923), 67–71 (2009). 10.1126/science.1170336
J. Bath, S. J. Green, A. J. Turberfield, Coordinated chemomechanical cycles: A mechanism for autonomous molecular motion. Phys. Rev. Lett. 101, 238101 (2008)
K. W. Plaxco, C. Fan, A. J. Heeger. Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA. Proc. Nat. Acad. Sci. 100(16), 9134–9137 (2003)
D. Lubrich, S.J. Green, A.J. Turberfield, DNA hairpins: Fuel for autonomous DNA devices. Biophys. J. 91(8), 2966–2975 (2006)
J.S. Bois, B.R. Wolfe, M.B. Pierce, A.R. Khan, R.M. Dirks, J.N. Zadeh, C.D. Steenberg, N.A. Pierce, Nupack: Analysis and design of nucleic acid systems. J. Comput. Chem. 32(1), 170–173 (2011)
W. N. Hunter, G. Kneale, T. Brown, O. Kennard. Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations. Proc. Natl. Acad. Sci. USA, 83(8), 2402–2406 (1986)
A.C. Gustafsson, F. Sterky, P. Nyrn, M. Uhln, A. Ahmadian, Baback Gharizadeh and J. Lundeberg. Single-nucleotide polymorphism analysis by pyrosequencing. Anal. Biochem. 280(1), 103–110 (2000)
G. Wang, Q. Chi, J. Jiang, The persistence length and length per base of single-stranded DNA obtained from fluorescence correlation spectroscopy measurements using mean field theory. Physica A 392(5), 1072–1079 (2013)
D. Langford, R. Bonand, E. Koutsoumpeli, J. Murray, S. Johnson, Probing molecular interactions with methylene blue derivatized self-assembled monolayers. Sens. BioSens. Res., pp. 1–6 (2015)
Z. Zhang F. Yang J. Wang, X. Xu and Xi. Yang. Real-time study of genomic dna structural changes upon interaction with small molecules using dual-polarization interferometry. Anal. Chem. 81(12), 4914–4921 (2009)
T.A. Jowitt, J. Ylstalo, P. Coffey, R.S. Meadows, L. Ala-Kokko, D.J. Thornton, M. Fresquet, M.D. Briggs, Structural and functional characterization of recombinant matrilin-3 a-domain and implications for human genetic bone diseases. J. Biol. Chem. 282(48), 34634–34643 (2007)
T.A. Waigh, F. Schedin, P.D. Coffey, M.J. Swann, J.R. Lu, Multiple path length dual polarization interferometry. Opt. Express 17(13), 10959–10969 (2009)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this chapter
Cite this chapter
Juan Colás, J. (2017). Tailoring Light-Matter Interaction for Quantification of Biological and Molecular Layers. In: Dual-Mode Electro-photonic Silicon Biosensors. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-60501-2_6
Download citation
DOI: https://doi.org/10.1007/978-3-319-60501-2_6
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-60500-5
Online ISBN: 978-3-319-60501-2
eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)