Ethnicity, Obesity, and Pregnancy Outcomes on Fetal Programming

  • Miranda Davies-Tuck
  • Mary-Ann Davey
  • Joel A. Fernandez
  • Maya Reddy
  • Marina G. Caulfield
  • Euan Wallace
Chapter
Part of the Nutrition and Health book series (NH)

Abstract

A number of diseases over the life course such as cardiovascular disease, diabetes, asthma, cancer, allergies, and neurocognitive impairment occur at differing rates among people of different ethnicities. There is growing evidence to suggest that this is a consequence of fetal programming. Gestational diabetes mellitus (GDM) and hypertensive conditions in pregnancy such as gestational hypertension and preeclampsia both occur at elevated rates in women of certain ethnicities. Women of different ethnicities also experience higher rates of adverse pregnancy outcomes and interventions including preterm birth, low birth weight/small for gestational age, and cesarean birth. All of the outcomes listed above have been linked to fetal programming and may explain the increased rates of chronic diseases among people of different ethnicities. Compounding the issue further are the increasing rates of maternal obesity experienced among women in high-income nations. Emerging evidence has suggested that the associations between obesity, adverse pregnancy outcomes, and life course diseases may also be additive in some ethnicities. Further research is needed to uncover specific mechanisms.

Keywords

Maternal ethnicity Pregnancy complications Pregnancy outcomes Obesity Fetal programing 

Abbreviations

BMI

Body mass index

CVD

Cardiovascular disease

DM

Diabetes mellitus

GDM

Gestational diabetes mellitus

HIC

High-income country

NICU

Neonatal intensive care unit

PE

Preeclampsia

UK

United Kingdom

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Miranda Davies-Tuck
    • 1
  • Mary-Ann Davey
    • 2
  • Joel A. Fernandez
    • 3
  • Maya Reddy
    • 4
  • Marina G. Caulfield
    • 5
  • Euan Wallace
    • 5
  1. 1.The Ritchie CentreHudson Institute of Medical ResearchClaytonAustralia
  2. 2.Department of Obstetrics and Gynaecology, School of Clinical SciencesMonash UniversityClaytonAustralia
  3. 3.Department of Obstetrics and GynaecologyMonash Medical CentreMelbourneAustralia
  4. 4.Monash HealthMonash Medical CentreClaytonAustralia
  5. 5.Department of Obstetrics and GynecologyMonash UniversityClaytonAustralia

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