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Higher Cortical Functions

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Abstract

 What is a higher cortical function? As one examines the abilities of a human, one is struck by our ability to use tools and create wonderful buildings or works of art. But our ability to communicate by speaking and writing and reading we believe is the best example of a higher cortical function. These centers that are responsible for language are primarily in the dominant hemisphere. The motor type of aphasia (Broca’s area) originates from the inferior frontal gyrus, while the sensory type of aphasia originates in the superior temporal gyrus (Wernicke’s area).

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General or Historical References

  • Ajamone-Marsan C, Ralston BL. The epileptic seizure: its functional morphology and diagnostic significance. Springfield: Charles C. Thomas; 1957.

    Google Scholar 

  • Alexander GE, DeLong MR. Central mechanisms of initiation and control of movement. In: Asbury AK, McKhann GM, McDonald WI, editors. Diseases of the nervous system: clinical neurobiology. 2nd ed. Philadelphia: W.B. Saunders; 1992. p. 285–308.

    Google Scholar 

  • Brumback RA, editor. Behavioral neurology. Neurol Clin. 1993;11:1–237.

    Google Scholar 

  • Chui H, Damasio A. Human cerebral asymmetries evaluated by computed tomography. J Neurol Neurosurg Psychiatr. 1980;43:873–8.

    Article  Google Scholar 

  • Cole J. Laterality in the use of eye, hand and foot in monkeys. J Comp Physiol Psychol. 1957;50:296–9.

    Article  CAS  PubMed  Google Scholar 

  • Commission on Classification and Terminology of the International League against Epilepsy. Proposal for re-revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia. 1981;22:489–501.

    Article  Google Scholar 

  • Commission on Classification and Terminology of the International League against Epilepsy. Proposal for a revised classification of epilepsies and epileptic syndromes. Epilepsia. 1989;30:389–99.

    Article  Google Scholar 

  • Corkin S, Milner B, Rasmussen T. Effects of different cortical excisions on sensory thresholds in man. Trans Amer Neurol Assoc. 1964;89:112–6.

    CAS  Google Scholar 

  • Coslett HB, editor. Behavioral neurology/higher cortical function. Semin Neurol. 2000a;20:405–515.

    Google Scholar 

  • Coslett HB. Acquired dyslexia. Semin Neurol. 2000b;20:419–26.

    Article  CAS  PubMed  Google Scholar 

  • Coslett HB, Saffran EM. Evidence for preserved reading in pure alexia. Brain. 1989;112:327–59.

    Article  PubMed  Google Scholar 

  • Coslett HB, Brashear HP, Heilman KM. Pure word deafness after bilateral primary auditory cortex infarcts. Neurology. 1984;34:347–52.

    Article  CAS  PubMed  Google Scholar 

  • Cracco RQ, Amassian VE, Maccabee PJ. Comparison of human transcallosal responses evoked by magnetic coil and electrical stimulation. Electroencephalogr Clin Neurophysiol. 1989;74:417–24.

    Article  CAS  PubMed  Google Scholar 

  • Damasio AR. The frontal lobes. In: Heilman KM, Valenstein E, editors. Clinical neuropsychology. 2nd ed. New York: Oxford; 1985. p. 339–75.

    Google Scholar 

  • Damasio AR. Medical progress: aphasia. N Engl J Med. 1992;326:531–9.

    Article  CAS  PubMed  Google Scholar 

  • Damasio H, Damasio A. The anatomical basis of conduction aphasia. Brain. 1980;103:337–50.

    Article  CAS  PubMed  Google Scholar 

  • Damasio H, Damasio AR. Lesion analysis in Neuropsychology. New York: Oxford University Press; 1989.

    Google Scholar 

  • Damasio AR, Geschwind N. The neural basis of language. Ann Rev Neurosci. 1984;7:127–47.

    Article  CAS  PubMed  Google Scholar 

  • Damasio H, Grabowski T, Frank R, et al. The return of Phineas gage: clues about the brain from the skullof a famous patient. Science. 1994;264:1102–5.

    Article  CAS  PubMed  Google Scholar 

  • De Renzi E. Disorders of visual recognition. Semin Neurol. 2000;20:479–86.

    Article  PubMed  Google Scholar 

  • Dellatolas G, Luciani S, Castresana A, et al. Pathologic left-handed: left-handedness correlatives in adult epileptics. Brain. 1993;116:1565–74.

    Article  PubMed  Google Scholar 

  • DeRenzi E, Luchelli F. Ideational apraxia. Brain. 1988;111:1173–85.

    Article  Google Scholar 

  • Duffner KR, Ahern LL, Weintraub S. Dissociated neglect behavior following sequential strokes in the right hemisphere. Ann Neurol. 1990;28:97–101.

    Article  Google Scholar 

  • Duffner KR, Mesulam MM, Scinto LFM, et al. The central role of prefrontal cortex in directing attentionto novel events. Brain. 2000;123:927–39.

    Article  Google Scholar 

  • Dusser de Barenne JG, McCulloch WS. Suppression of motor response obtained from area 4 bystimulation of area 4S. J Neurophysiol. 1941;4:311–23.

    Google Scholar 

  • Engel J Jr. Seizures and epilepsy. Philadelphia: F.A. Davis; 1989.

    Google Scholar 

  • Ettlinger FG, editor. Function of the corpus callosum. Boston: Little, Brown and Company; 1965.

    Google Scholar 

  • Fangel C, Kaada BR. Behavior “attention” and fear induced by cortical stimulation in the cat. Electroencephalogr Clin Neurophysiol. 1960;12:575–88.

    Article  CAS  PubMed  Google Scholar 

  • Feinberg TE, Farah MJ. Agnosias. In: Bradley WG, et al., editors. Neurology in clinical practice. Boston: Butterworth Heinemann; 2000. p. 131–9.

    Google Scholar 

  • Ferrier D. Experimental researches in cerebral physiology and pathology. Rep West Riding Lunatic Asylum. 1873;3:30–96.

    Google Scholar 

  • Fletcher PC, Henson RNA. Frontal lobes and human memory. Insights from functional neuroimaging Brain. 2001;124:849–81.

    CAS  PubMed  Google Scholar 

  • Foerster O. The motor cortex in the light of Hughlings Jackson’s doctrines. Brain. 1936;59:135–59.

    Article  Google Scholar 

  • Freund HJ. Differential effects of cortical lesions in humans. In: Bock G, O’Connor M, Marsh J, editors. Motor areas of the cerebral cortex: Ciba foundation symposium. No. 132. Chichester: Wiley; 1987. p. 269–81.

    Google Scholar 

  • Freund HJ, Hummelshein H. Lesions of the premotor cortex in man. Brain. 1985;108:697–733.

    Article  PubMed  Google Scholar 

  • Fried I, Materr C, Ojemann G, et al. Organization of visuospatial functions in human cortex: evidence from electrical stimulation. Brain. 1982;105:349–71.

    Article  CAS  PubMed  Google Scholar 

  • Friedman RB, Albert ML. Alexia. In: Heilman KM, Valestein E, editors. Clinical neuropsychology. 2nd ed. New York: Oxford University Press; 1985.

    Google Scholar 

  • Fulton JF. Physiology of the nervous system. 3rd ed. New York: Oxford University Press; 1949.

    Google Scholar 

  • Galaburda AM, LeMay M, Kemper TL, et al. Right-left asymmetries in the brain. Science. 1978;199:852–6.

    Article  CAS  PubMed  Google Scholar 

  • Gandevia SC, Burke D, McKeon B. The projection of muscle afferents from the hand to cerebral cortex in main. Brain. 1984;107:1–13.

    Article  PubMed  Google Scholar 

  • Gazzaniga MS, Bogen JE, Sperry RW. Observations on visual perception after disconnections of the cerebral hemispheres in man. Brain. 1965;88:221–36.

    Article  CAS  PubMed  Google Scholar 

  • Geier S, Bancaud J, Talairach J, et al. The seizures of frontal lobe epilepsy: a study of clinical manifestations. Neurology. 1977;27:951–8.

    Article  CAS  PubMed  Google Scholar 

  • Geschwind N. Disconnection syndromes in animals and man. Brain. 1965;88:237–94. 585–644

    Article  CAS  PubMed  Google Scholar 

  • Geschwind N. Aphasia. N Engl J Med. 1971;284:654–6.

    Article  CAS  PubMed  Google Scholar 

  • Geschwind N, Levitsky W. Human brain: left-right asymmetries in temporal speech region. Science. 1968;161:186–7.

    Article  CAS  PubMed  Google Scholar 

  • Geschwind N, Quadfasel FA, Segarra J. Isolation of the speech area. Neuropsychologia. 1968;6:327–40.

    Article  Google Scholar 

  • Goldman-Rakic PS. Motor control function of the prefrontal cortex. In: Bock G, O’Connor M, Marsh J, editors. Motor areas of the cerebral cortex Ciba foundation symposium. No. 132. Chichester: Wiley; 1987. p. 187–201.

    Google Scholar 

  • Grafman J, Vance SC, Weingartner H, et al. The effects of lateralized frontal lesion on mood regulation. Brain. 1986;109:1127–48.

    Article  PubMed  Google Scholar 

  • Green JR. Sir Victor Horsley: a centennial recognition of his impact on neuroscience and neurological surgery. BNI Quart. 1987;3:2–16.

    CAS  Google Scholar 

  • Halsband U, Freund HJ. Premotor cortex and conditional motor learning in man. Brain. 1990;113:207–22.

    Article  PubMed  Google Scholar 

  • Halsband U, Ito N, Tanji J, Freund HJ. The role of premotor cortex and the supplementary motor area in the temporal control of movement in man. Brain. 1993;116:243–66.

    Article  PubMed  Google Scholar 

  • Harlow JM. Recovery from the passage of an iron bar through the head. Mass Med Soc Publ. 1868;2:327–46.

    Google Scholar 

  • Hausser-Hauw C, Bancaud J. Gustatory hallucinations in epileptic seizures: electrophysiological, clinical and anatomical correlates. Brain. 1987;110:339–60.

    Article  PubMed  Google Scholar 

  • Heilman KM, Roth LJG. Apraxia. In: Heilman KM, Valenstein E, editors. Clinical neuropsychology. New York: Oxford University Press; 1985. p. 134–50.

    Google Scholar 

  • Heilman KM, Valenstein ED, editors. Clinical Neuropsychology. 2nd ed. New York: Oxford University Press; 1985.

    Google Scholar 

  • Heilman, KM, E. Valenstein and RT Watson. 2000. Neglect and related disorders. Semin Neurol 20: 463–470.

    Google Scholar 

  • Heilman KM, Watson RT, Valenstein E, et al. Localization of lesions in neglect. In: Kertesz A, editor. Localization in Neuropsychology. New York: Academic Press; 1983. p. 471–92.

    Google Scholar 

  • Helmstaedter C, Kurher M, Linke DB, Elger CE. Right hemisphere restution of language and memory functions in right hemisphere language dominant patients with left temporal lobe epilepsy. Brain. 1994;117:729–37.

    Article  PubMed  Google Scholar 

  • Kennard MA, Ectors L. Forced circling in monkeys following lesions of the frontal lobes. J Neurophysiol. 1938;1:45–54.

    Google Scholar 

  • Kertesz A, Geschwind N. Patterns of pyramidal decussation and their relationship to handedness. Arch Neurol. 1971;4:326–32.

    Article  Google Scholar 

  • Killackey H, Ebner F. Convergent projection of three separate thalamic nuclei into a single cortical area. Science. 1973;179:283–5.

    Article  CAS  PubMed  Google Scholar 

  • Kirsher HS. Aphasia. In: Bradley WG, et al., editors. Boston: Butterworth Heinemann; 2000. p. 141–159.

    Google Scholar 

  • Landis T, Regard M, Bliestel A, et al. Prosopagnosia and agnosia for non-canonical views: an autopsied case. Brain. 1988;111:1287–97.

    Article  PubMed  Google Scholar 

  • Legarda S, Jayakar P, Duchowny M, et al. Benign rolandic epilepsy: high central and low central subgroups. Epilepsia. 1994;35:1125–9.

    Article  CAS  PubMed  Google Scholar 

  • Lehman R, Andermann F, Olivier A, et al. Seizures with onset in the sensorimotor face area: clinical patterns and results of surgical treatment in 20 patients. Epilepsia. 1994;35:1117–24.

    Article  CAS  PubMed  Google Scholar 

  • Leiguarda RS, Marsden CD. Limb apraxias. Higher order disorders of sensori motro integration. Brain. 2000;123:860–79.

    Article  PubMed  Google Scholar 

  • Leiguarda R, Starkstein S, Berthier M. Anterior callosal hemorrhage: a partial interhemispheric disconnection syndrome. Brain. 1989;112:1019–37.

    Article  PubMed  Google Scholar 

  • LeMay M, Culebras A. Human brain morphologic differences in the hemispheres demonstrable by carotid arteriography. New Eng J Med. 1972;287:168–70. (see also N. Geschwind. 1972. Editorial. New Eng. J. Med. 187:194-195).

    Article  CAS  PubMed  Google Scholar 

  • LeMay M, Geschwind N. Asymmetries of the human cerebral hemispheres. In: Caramazza A, Zurif EB, editors. Language acquisition and breakdown. Baltimore: Johns Hopkins; 1978. p. 311–28.

    Google Scholar 

  • LeMay M, Kido DK. Asymmetries of the cerebral hemispheres on computed tomograms. J Comput Assist Tomogr. 1978;2:471.

    Article  CAS  Google Scholar 

  • Luders H, Lesser RP, Dinner DS, et al. The second sensory area in humans: evoked potential and electrical stimulation studies. Ann Neurol. 1985;17:177–84.

    Article  CAS  PubMed  Google Scholar 

  • Luders H, Lesser RP, Dinner DS, et al. Localization of cortical function: new information from extraoperative monitoring of patients with epilepsy. Epilepsia. 1988;29(Suppl 2):56–65.

    Article  Google Scholar 

  • Ludlow CL, Rosenberg JR, Fair C, et al. Brain lesions associated with nonfluent aphasia, fifteen years following penetrating head injury. Brain. 1986;109:55–80.

    Article  PubMed  Google Scholar 

  • Lynch JC, Mountcastle VB, Talbot WH, et al. Parietal lobe mechanisms for directed visual attention. J Neurophysiol. 1977;40:362–89.

    CAS  PubMed  Google Scholar 

  • Marcus EM, Watson CW, Simon SA. Behavioral correlates of acute bilateral symmetrical epileptogenic foci in monkey cerebral cortex. Brain Res. 1968;9:370–3.

    Article  CAS  PubMed  Google Scholar 

  • Marcus EM, Jacobson S, Watson CW, et al. An experimental model of “petit mal epilepsy” in the monkey: additional studies of the anterior premotor area. Trans. Amer. Neurol. Assoc. 1970;95:279–81.

    CAS  Google Scholar 

  • Meador KF, Watson RT, Bowers D, et al. Hypometria with hemispatial and limb motor neglect. Brain. 1986;109:293–305.

    Article  PubMed  Google Scholar 

  • Mesulam MM, Hoeser GWV, Pandya DN, et al. Limbic and sensory connections of the inferior parietal lobule (area PG) in the rhesus monkey. Brain Res. 1977;136:393–414.

    Article  CAS  PubMed  Google Scholar 

  • Meyer B-U, Roricht S, Gafin von Einsiedel H, et al. Inhibitory and excitatory interhemispheric transfers between motor cortical areas in normal humans and patients with abnormalities of the corpus callosum. Brain. 1995;118:429.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Boston, MA, USA

    Stanley Jacobson

  2. Jamaica Plain, MA, USA

    Elliott M. Marcus

  3. South Abington Twp., PA, USA

    Stanley Pugsley

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  1. Stanley Jacobson
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  2. Elliott M. Marcus
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Jacobson, S., Marcus, E.M., Pugsley, S. (2018). Higher Cortical Functions. In: Neuroanatomy for the Neuroscientist. Springer, Cham. https://doi.org/10.1007/978-3-319-60187-8_17

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