Osteoarthritis (OA) is considered the most common disorder of the musculoskeletal system and the greatest cause of disability all over the world. As a consequence to the population aging, the prevalence of OA has increased. Data obtained from the Framingham study place OA at the same level of both cardiovascular diseases and chronic obstructive pulmonary disease as the major cause of chronic physical disability. Because the prevalence of OA increases with aging, coexistence with other chronic diseases is common, further increasing the impact on the quality of life of those patients. The major comorbidities of OA patients include arterial hypertension, cardiovascular disease, diabetes, and dyslipidemia. Metabolic syndrome is defined as the association of hypertension, central obesity, glucose intolerance, and hyperlipidemia. On another front, as OA is the major cause of pain in older adult patients, a population with a very high prevalence of depression, the coexistence of both diseases is frequent. Although OA is the most common disease causing physical disability, the full impact of its combination with other chronic diseases, i.e., comorbidities, on the patients has not been thoroughly addressed. This chapter will discuss osteoarthritis epidemiology, manifestations, associated comorbidities, as well as management.


Osteoarthritis Osteoarthritis comorbidities Osteoarthritis imaging Osteoarthritis treatment Osteoarthritis and cardiovascular disease Osteoarthritis and diabetes Obesity and osteoarthritis 


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Laboratorio de Ultrasonido Musculoesqueletico y ArticularInstituto Nacional de RehabilitaciónCiudad de MéxicoMexico
  2. 2.Department of Epidemiology and BiostatisticsVU University Medical Center, EMGO Institute for Health and Care ResearchAmsterdamThe Netherlands
  3. 3.New Kasr El Aimi Teaching Hospital, Cairo UniversityCairoEgypt

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