Patient’s Guide: Helicobacter pylori in Peptic Ulcer Disease

  • Andrzej Wasilewski
  • Paula Mosińska


Helicobacter pylori infection can lead to the occurrence of many diseases of the upper gastrointestinal tract and is one of the most common causes of peptic ulcer disease (PUD). This discovery of H. pylori made possible not only to understand the origin of the disease, but also to use an appropriate treatment and prevent PUD recurrence.

Current guidelines do not recommend an active search for H. pylori infection in an asymptomatic population. Nevertheless, prevention of H. pylori infection is possible and even simple recommendations can minimize the spread of bacteria.

The following section contains information regarding epidemiology, transmission routes, symptoms of infection, and contribution of H. pylori into the development of PUD.


Gastric ulcer Helicobacter pylori Nonsteroidal anti-inflammatory drugs Peptic ulcer disease Virulence factors 



Cytotoxin-associated gene A






Mucosa associated lymphoid tissue lymphoma


Nonsteroidal anti-inflammatory drugs


Polymerase chain reaction


Proton pump inhibitors


Peptic ulcer disease


Rapid urease test


Stool antigen test


Urea breath test


Vacuolating cytotoxin A



The work is supported by grants from the Medical University of Lodz (#502-03/1-156-04/502-14-239 to AW, #502-03/1-156-04/502-14-299 to PM, and #503/1-156-04/503-11-001 to JF) and grant from National Science Centre [#UMO-2016/21/N/NZ5/01932 to PM].


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of Biochemistry, Faculty of MedicineMedical University of LodzLodzPoland

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