Abstract
Stimulant abuse, particularly methamphetamine, increased dramatically among women of childbearing age between 1994 and 2006; however, the rate of abuse has plateaued since and use during pregnancy is difficult to estimate. Maternal physiologic effects are similar to that of cocaine, with sympathetic system activation during periods of acute intoxication and significant psychosis with long-term use. Poorer obstetric and neonatal outcomes to include preterm delivery, placental abruption, and small for gestational age deliveries occur; however, long-term child outcomes appear similar to that of non-stimulant-abusing women. Intra- and postpartum obstetric management are similar to that of the cocaine-abusing mother. Neuraxial blockade may be complicated by more frequent and more difficult to treat hypotension due to catecholamine depletion in the chronic non-intoxicated abuser.
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References
Substance Abuse and Mental Health Services Administration. Results from the 2013 National Survey on Drug Use and Health: summary of national findings. NSDUH series H-48, HHS publication no. (SMA) 14-4863. Rockville: Substance Abuse and Mental Health Services Administration; 2014.
Arria AM, Derauf C, Lagasse LL, et al. Methamphetamine and other substance use during pregnancy: preliminary estimates from the Infant Development, Environment, and Lifestyle (IDEAL) study. Matern Child Health J. 2006;10:203–302.
American College of Obstetricians and Gynecologists. Committee opinion number 479: methamphetamine abuse in women of reproductive age. Obstet Gynecol. 2011;117:751–5.
Good MM, Solt I, Acuna JG, et al. Methamphetamine abuse during pregnancy: maternal and neonatal implications. Obstet Gynecol. 2010;116:330–4.
Della Grotta S, LaGasse LL, Arria AM, et al. Patterns of methamphetamine use during pregnancy: results from the Infant Development, Environment, and Lifestyle (IDEAL) study. Matern Child Health J. 2010;14:519–27.
Hyman SE. Addiction to cocaine and amphetamine. Neuron. 1996;16:901–4.
Rayburn WF, Bogenschutz MP. Pharmacotherapy for pregnant women with addictions. Am J Obstet Gynecol. 2004;191:1885–97.
Singer LT, Moore DG, Meeyoung O, et al. One year outcomes of prenatal exposure to MDMA and other recreational drugs. Pediatrics. 2012;130:407–13.
Reynolds EW, Bada HS. Pharmacology of drugs of abuse. Obstet Gynecol Clin North Am. 2003;30:501–22.
Frost EAM, Gist RS, Adriano E. Drugs, alcohol, pregnancy, and the fetal alcohol syndrome. Int Anesthesiol Clin. 2011;49:119–33.
American College of Obstetricians and Gynecologists. ACOG Committee opinion no. 422: at-risk drinking and illicit drug use: ethical issues in obstetric and gynecologic practice. Obstet Gynecol. 2008;112:1449–60.
Smith LM, LaGasse LL, Derauf C, et al. Prenatal methamphetamine use and neonatal neurobehavioral outcome. Neurotoxicol Teratol. 2008;24:17–23.
Lu HL, Johnson A, O’Hre ED, et al. Effects of prenatal methamphetamine exposure on verbal memory revealed with functional magnetic resonance imaging. J Dev Behav Pediatr. 2009;30:185–92.
McLafferty LP, Becker M, Dresner N, et al. Guidelines for the management of pregnant women with substance abuse disorders. Psychosomatics. 2016;57:115–30.
D’Apoito K. Breastfeeding and substance abuse. Clin Obstet Gynecol. 2013;56:202–11.
Hanzawa S, Nemoto M, Etoh S, et al. A case of amphetamine-induced down-regulation of the beta-adrenoceptor. Mausi. 2001;50:1242–5.
Kuczkowski KM. Anesthetic implications of drug abuse in pregnancy. J Clin Anesth. 2003;15:382–94.
Johnston RR, Way WL, Miller RD. Alteration of anesthetic requirement by amphetamine. Anesthesiology. 1972;36:357–63.
Sullivan JT. Substance abuse and the drug addicted mother. In: Suresh MS, Segal S, Preston RL, Fernando R, Mason CL, editors. Shnider and Levinson’s anesthesia for obstetrics. 5th ed. Baltimore: Wolters Kluwer; 2013. p. 683–98.
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Baysinger, C.L. (2018). Amphetamines and Other Stimulant Use. In: Mankowitz, S. (eds) Consults in Obstetric Anesthesiology. Springer, Cham. https://doi.org/10.1007/978-3-319-59680-8_6
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DOI: https://doi.org/10.1007/978-3-319-59680-8_6
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