Artificial Textile Reinforced Tubular Aortic Heart Valves—Multi-scale Modelling and Experimental Validation

  • Deepanshu Sodhani
  • R. Varun Raj
  • Jaan Simon
  • Stefanie Reese
  • Ricardo Moreira
  • Valentine Gesché
  • Stefan Jockenhoevel
  • Petra Mela
  • Bertram Stier
  • Scott E. Stapleton
Chapter
Part of the Lecture Notes in Applied and Computational Mechanics book series (LNACM, volume 84)

Abstract

Tissue engineered valvular implants are in development as living and remodelling prostheses to replace damaged native valves. To improve the mechanical properties of the valve, textile is used as a reinforcing scaffold. To predict the behaviour and optimize the structure of such composites, it is necessary to understand the behaviour of the underlying components. The current study seeks to test a multi-scale approach often used in the field of composites to evaluate the behaviour of knitted textile reinforced elastomeric composites. The complex textile structure is divided into simplified models at different levels/structural units. Virtual experiments are conducted at each of these levels and their responses are fit to appropriate isotropic and anisotropic hyperelastic material models. The simulation responses obtained by conducting virtual experiments on the repeating unit cell (RUC) of the composite are then compared with experimental results, resulting in good agreement. After experimental validation, the multi-scale approach is used to predict the behaviour of artificial heart valves.

Notes

Acknowledgements

This research was funded by the Integrated Interdisciplinary Institute of Technology for Medicine (\(\mathrm {I^3TM}\)) of RWTH Aachen University, through the Seed-Fund SF-14-04-08, “Hybrid scaffold for a transcatheter tissue engineered aortic valve”. Additional funding was provided by the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme FP7/2007-2013/ under REA grant agreement 317512.

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Deepanshu Sodhani
    • 1
  • R. Varun Raj
    • 1
  • Jaan Simon
    • 1
  • Stefanie Reese
    • 1
  • Ricardo Moreira
    • 2
  • Valentine Gesché
    • 3
  • Stefan Jockenhoevel
    • 2
    • 3
  • Petra Mela
    • 2
  • Bertram Stier
    • 4
  • Scott E. Stapleton
    • 5
  1. 1.Institute of Applied Mechanics, RWTH Aachen UniversityAachenGermany
  2. 2.Institute of Applied Medical Engineering, Helmholtz-Institute, RWTH Aachen UniversityAachenGermany
  3. 3.Institut Für Textiltechnik, RWTH Aachen UniversityAachenGermany
  4. 4.HypersizerNewport NewsUSA
  5. 5.Department of Mechanical EngineeringUniversity of Massachusetts LowellLowellUSA

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