Abstract
Most prostate biopsies are performed for an elevated prostate-specific antigen (PSA) level, a palpable nodule, or a history of an abnormal biopsy and are for the purpose of ruling out prostatic adenocarcinoma. In the prostate, you are generally looking only for carcinoma and other rare malignancies, as opposed to non-neoplastic processes. Prostatic adenocarcinoma is graded by the Gleason system, which is based on architectural pattern. Cytology (nuclear morphology) is pretty monotonous in prostate cancer and therefore does not affect grade. Pattern 3 is synonymous with well-differentiated carcinoma, and pattern 5 is poorly differentiated. This chapter covers the approach to the core biopsy and an introduction to the prostatic adenocarcinoma grading system, as well as the grossing strategy for the radical prostatectomy.
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© 2018 Springer International Publishing AG
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Molavi, D.W. (2018). Prostate. In: The Practice of Surgical Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-59211-4_11
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DOI: https://doi.org/10.1007/978-3-319-59211-4_11
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