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Metal Allergy pp 373-386 | Cite as

Metal Allergy: Copper

  • Simon W. Fage
Chapter

Abstract

Worldwide production of copper is increasing. Among other sources, human skin is exposed to copper from jewellery, coins, door fittings, knobs and taps. Mucosal exposure occurs through dental materials and copper-containing intrauterine contraceptive devices. Despite the fact that several studies show release of copper ions from different materials in a biological-like milieu, and although copper has many chemical similarities with nickel, a strong sensitizer, only few cases of copper allergy have been reported. Hence, copper seems to be a weak sensitizer that should be considered in select cases. Here we review the sources of exposure, chemistry, biology and cumulative data including case reports to clarify the implications of copper allergy.

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Dermato-VenereologyAarhus University HospitalAarhusDenmark

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