Abstract
The etiology of antidepressant discontinuation syndrome is not fully understood but it tends to occur after the abrupt discontinuation of an antidepressant, though may also occur even with a taper.It is known to occur with monoamine oxidize inhibitors (MAOI), tricyclic antidepressants (TCA), selective serotonin reuptake inhibitors (SSRI), serotonin-norepinephrine reuptake inhibitors (SNRI) and atypical antidepressants.The syndrome can occur with missing only one dose of medications with short half-lives, such as paroxetine and venlafaxine. Symptoms can last for weeks, sometimes longer.It is important to recognize this syndrome in order to avoid very costly work ups.
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Corbett, B., Nordstrom, K.D. (2018). Antidepressant Discontinuation Syndrome. In: Nordstrom, K., Wilson, M. (eds) Quick Guide to Psychiatric Emergencies. Springer, Cham. https://doi.org/10.1007/978-3-319-58260-3_45
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DOI: https://doi.org/10.1007/978-3-319-58260-3_45
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