The Management of Peyronie’s Disease

  • Fabio Castiglione
  • David J. Ralph
  • Giulio Garaffa


Peyronie’s disease (PD) was first described by Francois de la Peyronie (1678–1747), who reported a series of patients with “rosary beads of scar tissue” causing curvature of the penis. Peyronie’s Disease is an acquired benign fibrotic disorder involving the tunica albuginea (TA) of the corpora cavernosa of the penis leading to the formation of fibrous inelastic plaques [1]. Peyronie’s Disease is believed to occur in the genetically susceptible individuals and is associated with penile curvature, pain and worsening of erectile function. Peyronie’s Disease has an estimated prevalence of 3–9% in adult men and is frequently associated with cardiovascular risk factors including diabetes, hypertension, dyslipidaemia, and low serum testosterone levels [2–5].


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Fabio Castiglione
    • 1
  • David J. Ralph
    • 1
  • Giulio Garaffa
    • 1
  1. 1.Department of Urology, The Institute of UrologyUniversity College London HospitalsLondonUK

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