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The Use of Deep Learning for Segmentation of Bone Marrow Histological Images

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Artificial Intelligence Trends in Intelligent Systems (CSOC 2017)

Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 573))

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Abstract

Proposed solution gives the segmentation of bone marrow histological images, required for further analysis via different methods. Proposed algorithm is based on deep learning using Convolutional Neural Network. More then 50 of ConvNNs where tested with different configurations and learning parameters (learning rate, weight decay). Obtained effectiveness is more then 92%.

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References

  1. Bram, R.: Deep learning in histopathology. Technical report, VU University Amsterdam (2016)

    Google Scholar 

  2. Domagala, W., Chosia, M., Urasinska, E.: Atlas of histopathology. Wydawnictwo Lekarskie PZWL (2007)

    Google Scholar 

  3. Janowczyk, A., Madabhushi, A.: Deep learning for digital pathology image analysis: a comprehensive tutorial with selected use cases. J. Pathol. Inf. 7(1), 29 (2016)

    Article  Google Scholar 

  4. King, D.E.: Dlib-ml: a machine learning toolkit. J. Mach. Learn. Res. 10, 1755–1758 (2009)

    Google Scholar 

  5. Knapp, O.: Zastosowanie cyfrowej analizy obrazu do ilosciowej oceny histomorfometrycznej preparatow mikroskopowych. Ph.D. thesis, Szczecin (2009)

    Google Scholar 

  6. Knapp, O., Waloszczyk, P.: Ilosciowy opis preparatow histopatologicznych glow kosci udowych, w korelacji z wiekiem, przy zastosowaniu cyfrowego analizatora obrazu. Annales Academiae Medicae Stetinensis (2007)

    Google Scholar 

  7. Kraus, O.Z., Ba, J.L., Frey, B.J.: Classifying and segmenting microscopy images with deep multiple instance learning. Bioinformatics 32(12), i52 (2016)

    Article  Google Scholar 

  8. Kumar, B., Abbas, A.K., Aster, J.: Robbins Basic Pathology. Elsevier, Philadelphia (2013)

    Google Scholar 

  9. Kumar, V., Abbas, A.K., Aster, J.C.: Robbins & Cotran Pathologic Basis of Disease. Elsevier, Philadelphia (2015)

    Google Scholar 

  10. LeCun, Y., Kavukcuoglu, K., Farabet, C.: Convolutional networks and applications in vision. In: Proceedings of 2010 IEEE International Symposium on Circuits and Systems, pp. 253–256, May 2010

    Google Scholar 

  11. LeCun, Y., Bengio, Y., Hinton, G.: Deep learning. Nature 521(7553), 436–444 (2015)

    Article  Google Scholar 

  12. Li, W., Manivannan, S., Akbar, S., Zhang, J., Trucco, E., McKenna, S.J.: Gland segmentation in colon histology images using hand-crafted features and convolutional neural networks. In: 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), pp. 1405–1408, April 2016

    Google Scholar 

  13. Litjens, G., Snchez, C.I., Timofeeva, N., Hermsen, M., Nagtegaal, I., Kovacs, I., Hulsbergen van de Kaa, C., Bult, P., van Ginneken, B., van der Laak, J.: Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis. Sci. Rep. 6, 26286 (2016)

    Article  Google Scholar 

  14. Long, J., Shelhamer, E., Darrell, T.: Fully convolutional networks for semantic segmentation. In: IEEE Conference on Computer Vision and Pattern Recognition, CVPR 2015, Boston, MA, USA, 7–12 June 2015, pp. 3431–3440 (2015)

    Google Scholar 

  15. Malon, C., Miller, M., Burger, H.C., Cosatto, E., Graf, H.P.: Identifying histological elements with convolutional neural networks. In: Proceedings of the 5th International Conference on Soft Computing as Transdisciplinary Science and Technology, CSTST 2008, pp. 450–456. ACM, New York (2008)

    Google Scholar 

  16. Sirinukunwattana, K., Raza, S.E.A., Tsang, Y.W., Snead, D.R.J., Cree, I.A., Rajpoot, N.M.: Locality sensitive deep learning for detection and classification of nuclei in routine colon cancer histology images. IEEE Trans. Med. Imaging 35(5), 1196–1206 (2016)

    Article  Google Scholar 

  17. Sobotta, J.: Histology. Urban & Schwarzenberg (1983)

    Google Scholar 

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Acknowledgments

This work is supported by the UE EFRR ZPORR project Z/2.32/I/1.3.1/267 /05 “Szczecin University of Technology – Research and Education Center of Modern Multimedia Technologies” (Poland). We gratefully acknowledge the support of West–Pomeranian University of Technology, Szczecin (Department of Signal Processing and Multimedia Engineering).

We gratefully acknowledge the support of NVIDIA Corporation with the donation of the Titan X GPU used for this research.

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Correspondence to Dorota Oszutowska–Mazurek .

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Oszutowska–Mazurek, D., Knap, O. (2017). The Use of Deep Learning for Segmentation of Bone Marrow Histological Images. In: Silhavy, R., Senkerik, R., Kominkova Oplatkova, Z., Prokopova, Z., Silhavy, P. (eds) Artificial Intelligence Trends in Intelligent Systems. CSOC 2017. Advances in Intelligent Systems and Computing, vol 573. Springer, Cham. https://doi.org/10.1007/978-3-319-57261-1_46

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  • DOI: https://doi.org/10.1007/978-3-319-57261-1_46

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