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Eating Disorders in Adolescence

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Good Practice in Pediatric and Adolescent Gynecology

Abstract

Identification of eating disorders, especially atypical or with mild restrictions of food intake is a frequent challenge for clinicians working with adolescents. The knowledge of risk and promoting factors and a basic comprehension of metabolic and endocrine mechanisms involved in adaptation to energy deficiency is helpful for the diagnostic evaluation. The recommended management of ED is multidisciplinary integrating physical and psychological support.

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Abbreviations

ADH:

Anti diuretic hormone

ALMI:

Appendicular Lean Mass Index

AMH:

Anti-Mullerian hormone

AN:

Anorexia nervosa

ARFID:

Avoidant/restrictive food intake disorder

ARP:

Agouti-related protein

BCMI:

Body Cell Mass Index

BIA:

Body impedance assessment

BMC:

Bone mineral content

BMD:

(areal) Bone mineral density

BMI:

Body Mass Index

BN:

Bulimia nervosa

CCK:

Cholecystokinin

DSM:

Diagnostic and statistical manual of mental disorders

DXA:

Dual X-ray absorptiometry

ED:

Eating disorders

FFM:

Fat free mass

FSH:

Follicle-stimulating hormone

FT3 :

Free 3-jodo-thyronin

Gh:

Growth hormone

GI:

Gastrointestinal

GLP-1:

Glucagon-like peptide 1

GnRH:

Gonadotropin-releasing hormone

IGF-1:

Insulin-like growth factor

IGFBP:

Insulin-like growth factor binding protein

LH:

Luteotropic hormone

NPY:

Neuro peptide Y

PP:

Pancreatic polypeptide

REE:

Resting energy expenditure

SGOT:

Serum glutamic oxaloacetic transaminase

SHBG:

Sex hormone binding protein

SRIs:

Serotonin reuptake inhibitors

TBW:

Total body water

References

  1. Micali N, Ploubidis G, De Stavola B, Simonoff E, Treasure J. Frequency and patterns of eating disorders symptoms in early adolescence. J Adolesc Health. 2014;54:574–81.

    Article  PubMed  Google Scholar 

  2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM 5). Washington, DC: APA; 2013.

    Book  Google Scholar 

  3. Fuller-Thomson E, Sinclair DA, Brennenstuhl S. Carrying the pain of abuse: gender-specific findings on the relationship between childhood physical abuse and obesity in adulthood. Obes Facts. 2013;6:325–36.

    Article  PubMed  Google Scholar 

  4. Mason SM, Flint AJ, Filed AE, Austin SB, Rich-Edwards JW. Abuse victimization in childhood or adolescence and risk of food addiction in adult women. Obesity (Silver Spring). 2013;21(12):E775–81.

    Article  Google Scholar 

  5. Roa J, Garcia-Galiano D, Castellano GM, Gaytan F, Pinilla L, Tena-Sempere M. Metabolic control of puberty onset: new players, new mechanisms. Mol Cell Endocrinol. 2010;324:87–94.

    Article  CAS  PubMed  Google Scholar 

  6. De Bond JAP, Smith JT. Kisspeptin and energy balance in reproduction. Reproduction. 2014;147:R53–63.

    Article  PubMed  Google Scholar 

  7. Evans MC, Anderson GM. Neuroendocrine integration of nutritional signals on reproduction. J Mol Endocrinol. 2017;58:R107–28.

    Article  CAS  PubMed  Google Scholar 

  8. Loucks AB. The response of luteinizing hormone pulsatility to 5 days of low energy availability disappears by 14 years of gynecological age. J Clin Endocrinol Metab. 2006;91(8):3158–64.

    Article  CAS  PubMed  Google Scholar 

  9. Baskaran C, Eddy KT, Miller KK, Meenaghan E, Misra M, Lawson EA. Leptin secretory dynamics and associated disordered eating psychopathology across the weight spectrum. Eur J Endocrinol. 2016;174(4):503–12.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Repaci A, Gambineri A, Pagotto U, Pasquali R. Ghrelin and reproductive disorders. Mol Cell Endocrinol. 2011;340:70–9.

    Article  CAS  PubMed  Google Scholar 

  11. Wolfe A, Dival S, Wu S. The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1. Front Neuroendocrinol. 2014;35(4):558–72.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Misra M, Klibanski A. Endocrine consequences of anorexia nervosa. Lancet Diabetes Endocrinol. 2014;2(7):581–92.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Kyle U, Bosaeus I, De Lorenzo AD, Deurenberg P, et al. Bioelectrical impedance analysis- part I: review of principles and methods. Clin Nutr. 2004;23:1226–43.

    Article  PubMed  Google Scholar 

  14. Bruni V, Dei M, Morelli C, Schettino MT, Balzi D, Nuvolone D. Body composition variables and leptin levels in functional hypothalamic amenorrea and amenorrhea related to eating disorders. J Pediatr Adolesc Gynecol. 2011;24(6):347–52.

    Article  PubMed  Google Scholar 

  15. Oskis A, Loveday C, Hucklebridge F, Thorn L, et al. Diurnal patterns of salivary cortisol and DHEA in adolescent anorexia nervosa. Stress. 2012;15(6):601–7.

    Article  CAS  PubMed  Google Scholar 

  16. International Society for Clinical Densitometry (ISCD). Combined official position. 2015. www.iscd.org

  17. Mehler PS, Brown C. Anorexia nervosa - medical complications. J Eat Disord. 2015;3:11–9.

    Article  PubMed  PubMed Central  Google Scholar 

  18. National Clinical Practice Guidelines CG9 The British Psychological Society & The Royal Collge of Psychiatrists 2004.

    Google Scholar 

  19. Golden NH, Katzman DK, Sawyer SM, et al. Update on the medical management of eating disorders in adolescents. J Adolesc Health. 2015;56:370–5.

    Article  PubMed  Google Scholar 

  20. Lock J. Treatment of adolescent eating disorders: progresses and challenges. Minerva Psichiatr. 2010;51(3):207–13.

    PubMed  PubMed Central  Google Scholar 

  21. Marzola E, Nasser JA, Hashim SA, et al. Nutritional rehabilitation in anorexia nervosa: review of the literature and implications for treatment. BMC Psychiatry. 2013;13:290–303.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Seetharaman S, Golden N, Halpern-Felshern B, et al. Effect of a prior history of overweight on return of menses in adolescents with eating disorders. J Adolesc Health. 2017;60(4):469–71.

    Article  PubMed  Google Scholar 

  23. El Goch M, Gatti D, Calugi S, et al. The association between weight gain restoration and bone mineral density in adolescents with anorexia nervosa: a systematic review. Forum Nutr. 2016;8:769–81.

    Google Scholar 

  24. Golden NH, Lanzkowsky L, Schebendach J, et al. The effect of estrogen-progestin treatment on bone mineral density in anorexia nervosa. J Pediatr Adolesc Gynecol. 2002;15:135–43.

    Article  PubMed  Google Scholar 

  25. DiVasta AD, Feldman HA, Beck TJ, et al. Does hormone replacement normalize bone geometry in adolescents with anorexia nervosa? J Bone Miner Res. 2012;29(1):151–7.

    Article  Google Scholar 

  26. Grinspoon S, Thomas L, Miller K, et al. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J Clin Endocrinol Metab. 2002;87:2883–91.

    Article  CAS  PubMed  Google Scholar 

  27. Golden NH, Iglesias EA, Jacobson MS, et al. Alendronate for the treatment of osteopenia in anorexia nervosa: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab. 2005;90(6):3179–85.

    Article  CAS  PubMed  Google Scholar 

  28. Misra M, Katzman D, Miller KK, et al. Physiologic estrogen replacement increases bone density in adolescent girls with anorexia nervosa. Int J Eat Disord. 2011;49(3):276–92.

    Article  Google Scholar 

  29. Keating C. Sex differences precipitating anorexia nervosa in females: the estrogen paradox and a novel framework for targeting sex-specific neurocircuits and behavior. Curr Top Behav Neurosci. 2011;8:189–207.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Metella Dei M.D. .

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Bruni, V., Dei, M. (2018). Eating Disorders in Adolescence. In: Fulghesu, A. (eds) Good Practice in Pediatric and Adolescent Gynecology. Springer, Cham. https://doi.org/10.1007/978-3-319-57162-1_8

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  • DOI: https://doi.org/10.1007/978-3-319-57162-1_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-57161-4

  • Online ISBN: 978-3-319-57162-1

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