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The Next Generation of Hemorrhage Therapy

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Front Line Surgery

Abstract

The management of major bleeding has significantly improved over the course of time. Patients are no longer relegated to inferior hemorrhage control strategies strictly focused on applying pressure to the wound. Despite these advances, major bleeding remains the most common source of preventable death in both the battlefield and civilian settings. Devices and intervention strategies are continuously being researched and developed to decrease complications and death related to these serious injuries at the trauma scene, in transit, and at higher echelons of care. In addition, further understanding of the pathophysiology of hemorrhage has allowed for the development of novel strategies that work at the cellular and subcellular level to improve outcomes in the setting of massive hemorrhage. This chapter reviews some of the latest developments in hemorrhage therapy and provides perspective on emerging technologies in its management.

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Author information

Authors and Affiliations

  1. Department of General Surgery, University of Michigan Health System, Ann Arbor, MI, USA

    Vahagn C. Nikolian

  2. Department of Surgery, University of Michigan, 1500 E. Medical Center Drive, 2920 Taubman Center/5331, Ann Arbor, MI, 48109, USA

    Hasan B. Alam

Authors
  1. Vahagn C. Nikolian
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  2. Hasan B. Alam
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Corresponding author

Correspondence to Hasan B. Alam .

Editor information

Editors and Affiliations

  1. Madigan Army Medical Center Department of Surgery, Uniformed Services University, Tacoma, Washington, USA

    Matthew J. Martin,

  2. Division of Acute Care Surgery, Division of Bariatric Surgery, Thomas Jefferson University Hospitals, Paoli Hospital, The Lankenau Hospital, Philadelphia, Pennsylvania, USA

    Alec C. Beekley,

  3. Madigan Army Medical Center Department of Surgery, Uniformed Services University, Tacoma, Washington, USA

    Matthew J. Eckert

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© 2017 Springer International Publishing AG

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Nikolian, V.C., Alam, H.B. (2017). The Next Generation of Hemorrhage Therapy. In: Martin,, M., Beekley, , A., Eckert, M. (eds) Front Line Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-56780-8_45

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  • DOI: https://doi.org/10.1007/978-3-319-56780-8_45

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-56779-2

  • Online ISBN: 978-3-319-56780-8

  • eBook Packages: MedicineMedicine (R0)

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