Neuromuscular Disease: An Overview
Although most patients with neuromuscular diseases can be treated as outpatients, some of them complain rapid and progressive muscle weakness and represent real clinical emergencies. Being able to hypothesize the etiopathological mechanism of hyposthenia is essential from the earliest stages of access to an emergency department. In this regard the role of a neurologist in the emergency department is indispensable. A detailed analysis of all the conditions that may occur in an acute phase goes beyond the purpose of this book that is meant to be a quick reference in the daily management of neuromuscular emergencies. The book deals with the main neuromuscular diseases on the basis of anatomo-clinical localizations. We will analyze the diseases affecting the anterior horns of the spinal cord (tetanus) and those that affect the nerve roots and the nerves (GBS, multiple mononeuritis, porphyria), the neuromuscular junction (MG and botulism), and finally the muscles (rhabdomyolysis, malignant hyperthermia, periodic paralysis).