Advertisement

Retinal Pigment Epithelial Detachment in Systemic Disease

  • Horst HelbigEmail author
Chapter

Abstract

RPE detachment is in most cases associated with ocular disease such as AMD, CSC, and others. In rare cases, it may be caused by systemic changes primarily manifesting themselves in the choroid. It is important to recognize these systemic diseases correctly, since therapeutic strategies have to focus not only on ocular manifestations but also have to include the systemic changes.

References

  1. 1.
    Wolfensberger TJ, Tufail A. Systemic disorders associated with detachment of the neurosensory retina and retinal pigment epithelium. Curr Opin Ophthalmol. 2000;11(6):455–61.CrossRefPubMedGoogle Scholar
  2. 2.
    Mili-Boussen I, Letaief I, Dridi H, Ouertani A. Bilateral retinal pigment epithelium tears in acute Vogt-Koyanagi-Harada disease. Retin Cases Brief Rep. 2013;7(4):350–4. doi: 10.1097/ICB.0b013e3182964f68.PubMedGoogle Scholar
  3. 3.
    Hosoda Y, Uji A, Hangai M, Morooka S, Nishijima K, Yoshimura N. Relationship between retinal lesions and inward choroidal bulging in Vogt-Koyanagi-Harada disease. Am J Ophthalmol. 2014;157(5):1056–63. doi: 10.1016/j.ajo.2014.01.015.CrossRefPubMedGoogle Scholar
  4. 4.
    Lin D, Chen W, Zhang G, Huang H, Zhou Z, Cen L, Chen H. Comparison of the optical coherence tomographic characters between acute Vogt-Koyanagi-Harada disease and acute central serous chorioretinopathy. BMC Ophthalmol. 2014;14:87. doi: 10.1186/1471-2415-14-87.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Bourcier T, Lumbroso L, Cassoux N, Fardeau C, Lehoang P. Retinal pigment epithelial detachment: an unusual presentation in ocular sarcoidosis. Br J Ophthalmol. 1998;82(5):585.CrossRefPubMedGoogle Scholar
  6. 6.
    Salchow DJ, Weiss MJ. Retinal pigment epithelial detachment in sarcoidosis. Ocul Immunol Inflamm. 2006;14(4):245–8. doi: 10.1080/09273940600826489.CrossRefPubMedGoogle Scholar
  7. 7.
    Ernst BB, Lowder CY, Meisler DM, Gutman FA. Posterior segment manifestations of inflammatory bowel disease. Ophthalmology. 1991;98(8):1272–80.CrossRefPubMedGoogle Scholar
  8. 8.
    Felekis T, Katsanos K, Kitsanou M, Trakos N, Theopistos V, Christodoulou D, et al. Spectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: a prospective single-center study. Inflamm Bowel Dis. 2009;15(1):29–34. doi: 10.1002/ibd.20584.CrossRefPubMedGoogle Scholar
  9. 9.
    von Graefe A. Mitteilungen vermischten Inhalts: Beobachtungen über Akkomodation bei Linsendefekt, Muskelkrankheiten und Anomalien der iris. Albrecht Von Graefes Arch Ophthalmol. 1855;2:187–94.CrossRefGoogle Scholar
  10. 10.
    Siegrist A. Beitrag zur Kenntnis der Arteriosklerose der Augengefässe. Z Augenheilkunde. 1899;2(Suppl):36–7.Google Scholar
  11. 11.
    Elschnig A. Die diagnostische und prognostische Bedeutung der Netzhauterkrankungen bei nephritis. Wien Med Wochenschr. 1904;54:446–50.Google Scholar
  12. 12.
    AlTalbishi A, Khateb S, Amer R. Elschnig’s spots in the acute and remission stages in preeclampsia. Spectral-domain optical coherence tomographic features. Eur J Ophthalmol. 2015;25(5):e84–7. doi: 10.5301/ejo.5000586.PubMedGoogle Scholar
  13. 13.
    Hayreh SS, Servais GE, Virdi PS. Fundus lesions in malignant hypertension. VI. Hypertensive choroidopathy. Ophthalmology. 1986;93(11):1383–400.CrossRefPubMedGoogle Scholar
  14. 14.
    Kishi S, Tso MO, Hayreh SS. Fundus lesions in malignant hypertension. I. A pathologic study of experimental hypertensive choroidopathy. Arch Ophthalmol. 1985;103(8):1189–97.CrossRefPubMedGoogle Scholar
  15. 15.
    Song Y-s, Kinouchi R, Ishiko S, Fukui K, Yoshida A. Hypertensive choroidopathy with eclampsia viewed on spectral-domain optical coherence tomography. Graefes Arch Clin Exp Ophthalmol. 2013;251(11):2647–50. doi: 10.1007/s00417-013-2462-9.CrossRefPubMedGoogle Scholar
  16. 16.
    Baker PS, Garg SJ, Fineman MS, Chiang A, Alshareef RA, Belmont J, Brown GC. Serous macular detachment in Waldenström macroglobulinemia: a report of four cases. Am J Ophthalmol. 2013;155(3):448–55. doi: 10.1016/j.ajo.2012.09.018.CrossRefPubMedGoogle Scholar
  17. 17.
    Ogata N, Ida H, Takahashi K, Fukuchi T, Uyama M. Occult retinal pigment epithelial detachment in hyperviscosity syndrome. Ophthalmic Surg Lasers. 2000;31(3):248–52.PubMedGoogle Scholar
  18. 18.
    Basu S, Das T, Padhi TR. Serous retinal detachment and multiple retinal pigment epithelial detachments, following hemodialysis for multi-organ failure. Indian J Ophthalmol. 2010;58(3):261–2. doi: 10.4103/0301-4738.62670.CrossRefPubMedPubMedCentralGoogle Scholar
  19. 19.
    Gass JD. Bullous retinal detachment and multiple retinal pigment epithelial detachments in patients receiving hemodialysis. Graefes Arch Clin Exp Ophthalmol. 1992;230(5):454–8.CrossRefPubMedGoogle Scholar
  20. 20.
    Troiano P, Buccianti G. Bilateral symmetric retinal detachment and multiple retinal pigment epithelial detachments during haemodialysis. Nephrol Dial Transplant. 1998;13(8):2135–7.CrossRefPubMedGoogle Scholar
  21. 21.
    Awan MA, Grierson DJ, Walker S. Bilateral macular sub-retinal fluid and retinal pigment epithelial detachment associated with type 2 membrano-proliferative glomerulonephritis. Clin Exp Optom. 2008;91(5):476–9. doi: 10.1111/j.1444-0938.2008.00268.x.CrossRefPubMedGoogle Scholar
  22. 22.
    D’souza Y, Short CD, McLeod D, Bonshek RE. Long-term follow-up of drusen-like lesions in patients with type II mesangiocapillary glomerulonephritis. Br J Ophthalmol. 2008;92(7):950–3. doi: 10.1136/bjo.2007.130138.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department OphthalmologyUniversity Hospital RegensburgRegensburgGermany

Personalised recommendations