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A Shift from a Single to Multiple Meta-analyses


A meta-meta-analysis is a meta-analysis of multiple meta-analyses. In this chapter a meta-meta-analysis from the authors is performed for the purpose of re-assessment of the pitfalls of the original meta-analyses with increased power and sample size. Also a meta-meta-analysis, performed for meta-learning purposes by Juni et al., and published in the BMJ of 2001, is reviewed.


  • Publication Bias
  • Pool Effect
  • Pool Odds Ratio
  • Christmas Tree
  • Outlier Study

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  • More background, theoretical and mathematical information of meta-analyses is given in Statistics applied to clinical studies 5th edition, Chaps. 32–34 and 48, Springer Heidelberg Germany, 2012, from the same authors.

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Cleophas, T.J., Zwinderman, A.H. (2017). Meta-Meta-analysis. In: Modern Meta-Analysis. Springer, Cham.

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