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History of Antiphospholipid Antibody

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Antiphospholipid Syndrome

Abstract

If one adds molecular and biological science to clinical description, the history of antiphospholipid antibody (aPL) and antiphospholipid syndrome (APS) contains nine phases. We base this history on personal memory (primarily that of MDL) and on conversations with the early North American leaders, Samuel Rapaport, Lawrence Shulman, Sandor Shapiro, Donato Alarcon-Segovia, and Carl Alving; others have seen the history differently. The nine phases emphasize mechanistic studies as well as clinical ones. Although the North American view necessarily has a New World bias, we do not wish to understate the important contributions from Europe, Asia, South Africa, Australia, and Central and South America—it’s just that we have less personal experience with them. This history omits many investigators, papers, and contributions. For those omissions I (MDL) apologize.

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Authors and Affiliations

  1. Hospital for Special Surgery, Weill Cornell Medicine, Department of Rheumatology, New York, NY, USA

    Michael D. Lockshin

  2. The University of the West Indies, Mona, Kingston, Jamaica

    E. Nigel Harris

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  1. Michael D. Lockshin
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  2. E. Nigel Harris
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Correspondence to Michael D. Lockshin .

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Editors and Affiliations

  1. The Barbara Volcker Center for Women and Rheumatic Diseases, Associate Attending Physician, Hospital for Special Surgery, Associate Professor of Medicine, Weill Cornell Medicine, New York, New York, USA

    Doruk Erkan

  2. The Barbara Volcker Center for Women and Rheumatic Diseases, Attending Physician, Hospital for Special Surgery, Professor of Medicine and Obstetrics-Gynecology, Weill Cornell Medicine, New York, New York, USA

    Michael D. Lockshin

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Lockshin, M.D., Harris, E.N. (2017). History of Antiphospholipid Antibody. In: Erkan, D., Lockshin, M. (eds) Antiphospholipid Syndrome. Springer, Cham. https://doi.org/10.1007/978-3-319-55442-6_1

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  • DOI: https://doi.org/10.1007/978-3-319-55442-6_1

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