• Rosangela Correa Villar
  • Thomas E. MerchantEmail author


Childhood ependymoma is an aggressive malignant brain tumor that affects a vulnerable group of patients. Young age at presentation, tumor and surgery related morbidity, and tumor association with critical normal tissue structures create a formidable challenge for the pediatric radiation oncologist. The use of advanced methods of radiation therapy in clinical trials during the past 20 years has improved disease and functional outcomes for these patients and provided an example for the treatment of other tumors that affect children in a similar manner. An improved understanding of the biology of ependymoma may impact future treatment decisions and the sequencing of irradiation as well as radiation dose and volume.


Ependymoma Brain tumor Pediatrics Radiotherapy Proton therapy 


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Rosangela Correa Villar
    • 1
    • 2
  • Thomas E. Merchant
    • 3
    Email author
  1. 1.Radiation Oncology Department, Centro Infantil Dr. Domingo A. BoldriniUniversity of CampinasCampinasBrazil
  2. 2.Radiation Oncology Department, Institute of Radiology, Hospital das ClinicasUniversity of Sao Paulo1270, Dr. Gabriel Porto Street, CampinasBrazil
  3. 3.Department of Radiation OncologySt. Jude Children’s Research HospitalMemphisUSA

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