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Choroid Plexus Tumors

  • Arthur K. LiuEmail author
  • Todd Hankinson
  • Johannes E. A. Wolff
Chapter

Abstract

Choroid plexus tumors (CPTs) are rare tumors of childhood and include choroid plexus papillomas (CPPs), atypical choroid plexus papilloma (aCPP), and choroid plexus carcinoma (CPC). CPTs often have mutations in TP53 and CPC is seen in patients with Li-Fraumeni syndrome. CPTs have relatively common characteristics on MRI. Management is primarily surgical for CPP, with chemotherapy and radiation generally reserved for CPTs that recur, or aCPP and CPC. Outcomes for CPP are very good with nearly all children cured with surgery. In contrast, CPC survival at 5 years ranges from 30 to 60%. Current studies are examining novel chemotherapy regimens.

Keywords

Choroid plexus tumor Choroid plexus papillomas Choroid plexus carcinoma 

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Arthur K. Liu
    • 1
    Email author
  • Todd Hankinson
    • 2
  • Johannes E. A. Wolff
    • 3
  1. 1.Department of Radiation OncologyUniversity of ColoradoAuroraUSA
  2. 2.Division of Pediatric NeurosurgeryUniversity of Colorado, Children’s Hospital ColoradoAuroraUSA
  3. 3.Department of Pediatric Hematology Oncology and Blood and Marrow TransplantationCleveland Clinic Children’sClevelandUSA

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