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Irreversible Electroporation of Kidney Tumours

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Irreversible Electroporation in Clinical Practice

Abstract

While there are numerous options for treatment of small (<4 cm) renal masses, irreversible electroporation (IRE) is a unique method of ablation which is reliable, safe and effective. Unlike other ablation methods, there is no need to cool the ureter or separate the colon from the kidney by injecting fluid into the perinephric space. Even when lesions extend into the central portion of the kidney, IRE is not associated with significant bleeding or haematuria. IRE is especially effective in the elderly or those with impaired renal function.

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References

  1. American Cancer Society. Cancer facts and figures 2000. Atlanta: American Cancer Society; 2000. p. 4.

    Google Scholar 

  2. Russo P. Renal cell carcinoma: presentation, staging, and surgical treatment. Semin Oncol. 2000;27:160–76. Medline.

    CAS  PubMed  Google Scholar 

  3. Cohan RH, Sherman LS, Korobkin M, Bass JC, Francis IR. Renal masses: assessment of corticomedullary-phase and nephrographic-phase CT scans. Radiology. 1995;196:445–51. Link.

    Article  CAS  PubMed  Google Scholar 

  4. Kopka L, Fischer U, Zoeller G, Schmidt C, Ringert RH, Grabbe E. Dual-phase helical CT of the kidney: value of the corticomedullary and nephrographic phase for evaluation of renal lesions and preoperative staging of renal cell carcinoma. AJR Am J Roentgenol. 1997;169:1573–8. CrossRef, Medline.

    Article  CAS  PubMed  Google Scholar 

  5. Szolar DH, Kammerhuber F, Altziebler S, et al. Multiphasic helical CT of the kidney: increased conspicuity for detection and characterization of small (<3-cm) renal masses. Radiology. 1997;202:211–7. Link.

    Article  CAS  PubMed  Google Scholar 

  6. Yuh BI, Cohan RH. Different phases of renal enhancement: role in detecting and characterizing renal masses during helical CT. AJR Am J Roentgenol. 1999;173:747–55. CrossRef, Medline.

    Article  CAS  PubMed  Google Scholar 

  7. Silverman SG, Lee BY, Seltzer SE, Bloom DA, Corless CL, Adams DF. Small (<3-cm) renal masses: correlation of spiral CT features and pathologic findings. AJR Am J Roentgenol. 1994;163:597–605. Cros allsRef, Medline.

    Article  CAS  PubMed  Google Scholar 

  8. Pech M1, Janitzky A, Wendler JJ, Strang C, Blaschke S, Dudeck O, Ricke J, Liehr UB. Irreversible electroporation of renal cell carcinoma: a first-in-man phase I clinical study. Cardiovasc Intervent Radiol. 2011;34:132–8.

    Article  PubMed  Google Scholar 

  9. Wagstaff P, de Bruin DM, Zondervan PJ, Heijink CD, Engelbrecht MRW, van Delden OM, van Leeuwen TG, Wijkstra H, de la Rosette JJ, Pes MP. The efficacy and safety of irreversible electroporation for the ablation of renal masses: a prospective, human, in-vivo study protocol. BMC Cancer. 2015;15:165.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Deodhar A, Monette S, Single GW Jr, Hamilton WC Jr, Thornton R, Maybody M, Coleman JA, Solomon SB. Renal tissue ablation with irreversible electroporation. Preliminary results in a porcine model. Urology. 2011;77:754–60.

    Article  PubMed  Google Scholar 

  11. Trimmer CK, Khosla A, Morgan M, Stephenson SL, Ozayar A, Cadeddu JA. Minimally invasive percutaneous treatment of small renal tumours with irreversible electroporation: a single centre experience. JVIR. 2015;26:1465–71.

    Article  PubMed  Google Scholar 

  12. Wehle MJ, Thiel DD, Petrou SP, Young PR, Frank I, Karsteadt N. Conservative management of incidental contrast-enhancing renal masses as safe alternative to invasive therapy. Urology. 2004;64:49–52.

    Article  PubMed  Google Scholar 

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Correspondence to Kenneth R. Thomson .

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Koukounaras, J., Kavnoudias, H., Thomson, K.R. (2018). Irreversible Electroporation of Kidney Tumours. In: Meijerink, M., Scheffer, H., Narayanan, G. (eds) Irreversible Electroporation in Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-319-55113-5_13

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  • DOI: https://doi.org/10.1007/978-3-319-55113-5_13

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