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Advantages and Limitations

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PET/CT in Radiotherapy Planning

Part of the book series: Clinicians’ Guides to Radionuclide Hybrid Imaging ((PET/CT))

Abstract

CT alone has conventionally informed radiotherapy planning. It provides anatomical information for delineation and electron density for dose calculation. Integrating PET-CT for radiotherapy planning offers the opportunity to individualize treatment and improve patient outcome. PET-CT’s molecular insight of tumour biology could facilitate a move away from ‘one-size-fits-all’ prescription to more accurate personalized radiotherapy [1].

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References

  1. Mankoff DA. A definition of molecular imaging. J Nucl Med. 2007;48(6):18N–21N.

    PubMed  Google Scholar 

  2. De Ruysscher D, Kirsch CM. PET scans in radiotherapy planning of lung cancer. Radiother Oncol. 2010;96(3):335–8.

    Article  PubMed  Google Scholar 

  3. Chiti A, Kirienko M, Gregoire V. Clinical use of PET-CT data for radiotherapy planning: what are we looking for? Radiother Oncol. 2010;96(3):277–9.

    Article  PubMed  Google Scholar 

  4. Hockel M, Schlenger K, Aral B, Mitze M, Schaffer U, Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 1996;56(19):4509–15.

    CAS  PubMed  Google Scholar 

  5. Thorwarth D, Geets X, Paiusco M. Physical radiotherapy treatment planning based on functional PET-CT data. Radiother Oncol. 2010;96(3):317–24.

    Google Scholar 

  6. Coffey M, Vaandering A. Patient setup for PET-CT acquisition in radiotherapy planning. Radiother Oncol. 2010;96(3):298–301.

    Google Scholar 

  7. Scripes PG, Yaparpalvi R. Technical aspects of positron emission tomography/computed tomography in radiotherapy treatment planning. Semin Nucl Med. 2012;42(5):283–8.

    Article  PubMed  Google Scholar 

  8. Bettinardi V, Picchio M, Di Muzio N, Gianolli L, Gilardi MC, Messa C. Detection and compensation of organ/lesion motion using 4D-PET-CT respiratory gated acquisition techniques. Radiother Oncol. 2010;96(3):311–6.

    Google Scholar 

  9. Weber WA. Quantitative analysis of PET studies. Radiother Oncol. 2010;96(3):308–10.

    Article  PubMed  Google Scholar 

  10. Nestle U, Schaefer-Schuler A, Kremp S, Groeschel A, Hellwig D, Rube C, Kirsch CM. Target volume definition for 18F-FDG PET-positive lymph nodes in radiotherapy of patients with non-small cell lung cancer. Eur J Nucl Med Mol Imaging. 2007;34(4):453–62.

    Article  PubMed  Google Scholar 

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Acknowledgements

We acknowledge NHS funding to the NIHR Biomedical Research Centre for Cancer and to Cancer Research UK (CRUK).

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Correspondence to Shaista Hafeez .

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Hafeez, S., Huddart, R. (2017). Advantages and Limitations. In: Chua, S. (eds) PET/CT in Radiotherapy Planning . Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-319-54744-2_6

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  • DOI: https://doi.org/10.1007/978-3-319-54744-2_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-54743-5

  • Online ISBN: 978-3-319-54744-2

  • eBook Packages: MedicineMedicine (R0)

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