Abstract
Current NCCN guidelines only recommend imaging at the time of presentation in stage 1 and 2 melanoma in cases with specific signs and symptoms due to low yield and frequent false positives. In stages 3 and 4, imaging is performed at baseline and in follow-up for assessment of response, detection of recurrence and complications of treatment [1]. Image-guided biopsy is also often needed to confirm metastases or recurrence and, depending on the location of the lesion, may be performed under CT or ultrasound guidance. The imaging manifestations of melanoma and the relative merits and weakness of different conventional imaging modalities are discussed below.
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NCCN Clinical Practice Guidelines in Oncology- Melanoma, version 1 2017. http://www.nccn.org/professionals/physician_gls/PDF/melanoma.pdf
Terhune MH, Swanson N, Johnson TM. Use of chest radiography in the initial evaluation of patients with localised melanoma. Arch Dermatol. 1998;134:569–72.
Michael King D. Imaging of metastatic melanoma. Cancer Imaging. 2006;6:204–8.
Vilana R, Puig S, Sanchez M, Squarcia M, Lopez A, Castel T, Malvehy J. Preoperative assessment of cutaneous melanoma thickness using 10-MHz sonography. AJR Am J Roentgenol. 2009;193(3):639–43.
Machet L, Nemeth-Normand F, Giraudeau B, et al. Is ultrasound lymph node examination superior to clinical examination in melanoma follow-up? A monocentre cohort study of 373 patients. Br J Dermatol. 2005;152:66–70.
Rossi CR, Mocellin S, Scagnet B, et al. The role of preoperative ultrasound scan in detecting lymph node metastasis before sentinel node biopsy in melanoma patients. J Surg Oncol. 2003;83:80–4.
Patnana M, Bronstein Y, Szklaruk J, Bedi DG, Hwu WJ, Gershenwald JE, Prieto VG, Ng CS. Multimethod imaging, staging, and spectrum of manifestations of metastatic melanoma. Clin Radiol. 2011;66(3):224–36.
Fishman EK, Kuhlman JE, Schuchter LM, et al. CT of malignant melanoma in the chest, abdomen, and musculoskeletal system. RadioGraphics. 1990;10:603–20.
Chen JT, Dahmash NS, Ravin CE, et al. Metastatic melanoma to the thorax: report of 130 patients. AJR Am J Roentgenol. 1981;137:293–8.
Kochhar R, Ali H, Mak S, Manoharan P. Metastatic cutaneous malignant melanoma: spectrum of imaging findings and the role of multimodality imaging. J Med Imaging Radiat Oncol. 2009;53(5):467–78.
Ginaldi S, Wallace S, Shalen P, et al. Cranial computed tomography of malignant melanoma. AJR Am J Roentgenol. 1981;136(1):145–9.
Escott EJ. A variety of appearances of malignant melanoma in the head: a review. Radiographics. 2001;21:625–39.
Premkumar A, Sanders L, Marincola F, Feuerstein I, Concepcion R, Schwartzentruber D. Visceral metastases from melanoma: findings on MR imaging. AJR Am J Roentgenol. 1992;158(2):293–8.
Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 2009;45:228–47. doi:10.1016/j.ejca.2008.10.026.
Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbé C, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009;15(23):7412–20. doi:10.1158/1078-0432.CCR-09-1624.
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Parameswaran, B.K., Eddie Lau, W.F. (2017). Radiological Imaging in Melanoma. In: Hofman, M., Hicks, R. (eds) PET/CT in Melanoma. Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-319-54741-1_4
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DOI: https://doi.org/10.1007/978-3-319-54741-1_4
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