Control, Prevention and Rapid Detection of Methicillin-Resistant Staphylococcus aureus

  • Sabah A. A. JassimEmail author
  • Richard G. Limoges


Methicillin-resistant Staphylococcus aureus (MRSA) infections are a particular problem in hospitals. Wild phages can be reprogrammed for several clinical isolates of MRSA. These phages can then be utilized in a safe fogging biocontrol system, using specialized dispensers, along with another non toxic liquid variation as a surface disinfectant in healthcare or animal settings for the decontamination of MRSA and other antibiotic resistant bacteria. This phage-based biocontrol technology is non-toxic, odourless, inexpensive and effective in controlling and reducing the risk of contracting a hospital-acquired MRSA infection. By using phages as a biocontrol in medical facilities both staff and patients can feel safe from MRSA. This chapter will demonstrate the benefits of phage-based MRSA decontamination coupled with several rapid bacterial detection protocols enabling the development of inexpensive diagnostic kits and safe decontamination methods. There is also an urgent need for a real-time, accurate and inexpensive diagnostic kit that can be used in situ with no need for skilled technicians while also allowing patients to test for some diseases or conditions at home. These tests are cost-effective, quick, and confidential. The aim of this chapter is to provide a comprehensive overview of some innovative phage biocontrol methodologies and diagnostic kits that can be used in healthcare settings, while encouraging further research on the use of phages diagnostically and preventatively in daily decontamination practices.


Bacteriophage Biocontrol Diagnostic Endolysins enzymes Epidemiology Farm animals Food Hospitals Infections Livestock Methicillin-resistant Staphylococcus aureus Methicillin-resistant coagulase-negative staphylococci Poultry Staphylococci 


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© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Applied Bio Research Inc.WindsorCanada

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