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Mucosal Lesions in Skin of Color

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Dermatoanthropology of Ethnic Skin and Hair

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Abstract

Mucosal surfaces are unique clinically and histologically. Certain diseases are more common or more noticeable in the mucosa of people with skin of color. Occasionally, there is ethnic variation in disease outcome as well. This section will focus on lesions within the oral mucosa.

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References

  1. Hoang MPSM. Vulvar Pathology. In: Hoang MP, Selim MA, editors. New York: Springer; 2015.

    Google Scholar 

  2. Woo S-B. Oral Pathology. 1st ed. Philadephia: Elsevier; 2012.

    Google Scholar 

  3. Feller L, Masilana A, Khammissa RA, Altini M, Jadwat Y, Lemmer J. Melanin: the biophysiology of oral melanocytes and physiological oral pigmentation. Head Face Med. 2014;10(8):8.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Meleti M, Vescovi P, Mooi WJ, van der Waal I. Pigmented lesions of the oral mucosa and perioral tissues: a flow-chart for the diagnosis and some recommendations for the management. Oral Sur Oral Med Oral Pathol Oral Radiol Endodontol. 2008;105(5):606–16.

    Article  Google Scholar 

  5. Müller S. Melanin-associated pigmented lesions of the oral mucosa: presentation, differential diagnosis, and treatment. Dermatol Therapy. 2010;23(3):220–9.

    Article  Google Scholar 

  6. Lenane P, Powell FC. Oral pigmentation. J Eur Acad Dermatol Venereol. 2000;14(6):448–65.

    Article  CAS  PubMed  Google Scholar 

  7. Weedon D. Weedon’s skin pathology. Elsevier; 2010.

    Google Scholar 

  8. Contreras E, Carlos R. Oral melanoacanthosis (melanoachantoma): report of a case and review of the literature. Med oral Patolo Oral Cir Bucal. 2004;10(1):11–2.

    Google Scholar 

  9. Brooks JK, Sindler AJ, Scheper MA. Oral Melanoacanthoma in an Adolescent. Pediatr Dermatol. 2010;27(4):384–7.

    Article  PubMed  Google Scholar 

  10. Cantudo-Sanagustín E, Gutiérrez-Corrales A, Vigo-Martínez M, Serrera-Figallo MÁ, Torres-Lagares D, Gutiérrez-Pérez JL. Pathogenesis and clinicohistopathological caractheristics of melanoacanthoma: a systematic review. J Clin Exp Dentistry. 2016;8(3):e327.

    Google Scholar 

  11. Behura SS. Oral mucosal lesions associated with smokers and chewers–a case-control study in chennai population. J Clin Diagnostic Res: JCDR. 2015;9(7):ZC17–22.

    Google Scholar 

  12. Marakoglu K, Gursoy UK, Toker HC, Demirer S, Sezer RE, Marakoglu I. Smoking status and smoke-related gingival melanin pigmentation in army recruitments. Mil Med. 2007;172(1):110–3.

    Article  PubMed  Google Scholar 

  13. Bellew SG, Alster TS. Treatment of exogenous ochronosis with a Q-switched alexandrite (755 nm) laser. Dermatol Sur. 2004;30(4):555–8.

    Google Scholar 

  14. Hassona Y, Sawair F, Al-karadsheh O, Scully C. Prevalence and clinical features of pigmented oral lesions. Int J Dermatol. 2016;55(9):1005–13.

    Article  PubMed  Google Scholar 

  15. Hedin CA, Pindborg JJ, Axell T. Disappearance of smoker’s melanosis after reducing smoking. J Oral Pathol Med. 1993;22(5):228–30.

    Article  CAS  PubMed  Google Scholar 

  16. Amano H, Tamura A, Yasuda M, et al. Amalgam tattoo of the oral mucosa mimics malignant melanoma. J Dermatol. 2011;38(1):101–3.

    Article  PubMed  Google Scholar 

  17. Ricart J, Martin JM. Acquired amalgam tattoo. A possible diagnostic pitfall. J Cosmet Dermatol. 2011;10(1):70–1.

    Article  PubMed  Google Scholar 

  18. Meleti M, Mooi WJ, Casparie MK, van der Waal I. Melanocytic nevi of the oral mucosa—no evidence of increased risk for oral malignant melanoma: an analysis of 119 cases. Oral Oncol. 2007;43(10):976–81.

    Article  PubMed  Google Scholar 

  19. Ferreira L, Jham B, Assi R, Readinger A, Kessler HP. Oral melanocytic nevi: a clinicopathologic study of 100 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;120(3):358–67.

    Article  PubMed  Google Scholar 

  20. Mohan M, Sukhadia VY, Pai D, Bhat S. Oral malignant melanoma: systematic review of literature and report of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;116(4):e247–54.

    Article  PubMed  Google Scholar 

  21. McLaughlin CC, Wu XC, Jemal A, Martin HJ, Roche LM, Chen VW. Incidence of noncutaneous melanomas in the U.S. Cancer. 2005;103(5):1000–7.

    Article  PubMed  Google Scholar 

  22. Altieri L, Wong MK, Peng DH, Cockburn M. Mucosal melanomas in the racially diverse population of California. J Am Acad Dermatol. 2017;76(2):250–7.

    Article  PubMed  Google Scholar 

  23. Ulusal BG, Karatas O, Yildiz AC, Oztan Y. Primary malignant melanoma of the maxillary gingiva. Dermatol Surg. 2003;29(3):304–307. http://www.ncbi.nlm.nih.gov/pubmed/12614430.

  24. Chatzistefanou I, Kolokythas A, Vahtsevanos K, Antoniades K. Primary mucosal melanoma of the oral cavity: current therapy and future directions. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122(1):17–27.

    Article  PubMed  Google Scholar 

  25. Lamichhane NS, An J, Liu Q, Zhang W. Primary malignant mucosal melanoma of the upper lip: a case report and review of the literature. BMC Res Notes. 2015;8(1):499.

    Article  PubMed  Google Scholar 

  26. Madani FM, Kuperstein AS. Normal variations of oral anatomy and common oral soft tissue lesions. Med Clin North Am. 2014;98(6):1281–98.

    Article  PubMed  Google Scholar 

  27. Martin JL. Leukoedema: an epidemiological study in white and African Americans. J Tenn Dent Assoc. 1997;77(1):18-21. http://www.ncbi.nlm.nih.gov/pubmed/9520752.

  28. Castellanos JL, Díaz-Guzmán L. Lesions of the oral mucosa: an epidemiological study of 23785 Mexican patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105(1):79–85.

    Article  PubMed  Google Scholar 

  29. Arakeri G, Brennan PA. Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management. Br J Oral Maxillofac Surg. 2013;51(7):587–93.

    Article  PubMed  Google Scholar 

  30. Aziz SR. Oral submucous fibrosis: case report and review of diagnosis and treatment. J Oral Maxillofac Surg. 2008;66(11):2386–9.

    Article  PubMed  Google Scholar 

  31. Angadi PV, Rao SS. Areca nut in pathogenesis of oral submucous fibrosis: Revisited. Oral Maxillofac Surg. 2011;15(1):1–9.

    Article  PubMed  Google Scholar 

  32. Tilakaratne WM, Klinikowski MF, Saku T, Peters TJ, Warnakulasuriya S. Oral submucous fibrosis: review on aetiology and pathogenesis. Oral Oncol. 2006;42(6):561–8.

    Article  CAS  PubMed  Google Scholar 

  33. Weatherspoon DJ, Chattopadhyay A, Boroumand S, Garcia I. Oral cavity and oropharyngeal cancer incidence trends and disparities in the United States: 2000-2010. Cancer Epidemiol. 2015;39(4):497–504.

    Article  PubMed  PubMed Central  Google Scholar 

  34. . Idris A, Vani N, Saleh S, et al. Relative Frequency of Oral Malignancies and Oral Precancer in the Biopsy Service of Jazan Province, 2009-2014. Asian Pac J Cancer Prev. 2016;17(2):519–525. http://www.ncbi.nlm.nih.gov/pubmed/26925637.

  35. Lewin F, Norell SE, Johansson H, et al. Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: a population-based case-referent study in Sweden. Cancer. 1998;82(7):1367–75.

    Article  CAS  PubMed  Google Scholar 

  36. Walker B, Figgs LW, Zahm SH. Differences in cancer incidence, mortality, and survival between African Americans and whites. Environ Health Perspect. 1995;103:275–81.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Joseph LJ, Goodman M, Higgins K, et al. Racial disparities in squamous cell carcinoma of the oral tongue among women: a SEER data analysis. Oral Oncol. 2015;51(6):586–92.

    Article  PubMed  Google Scholar 

  38. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin. 2015;65(1):5–29.

    Article  PubMed  Google Scholar 

  39. Sciubba JJ. Oral cancer. The importance of early diagnosis and treatment. Am J Clin Dermatol. 2001;2(4):239–251. http://www.ncbi.nlm.nih.gov/pubmed/11705251.

  40. Abu-Ghanem S, Yehuda M, Carmel NN, Leshno M, Abergel A, Gutfeld O, Fliss DM. Elective neck dissection vs observation in early-stage squamous cell carcinoma of the oral tongue with no clinically apparent lymph node metastasis in the neck: a systematic review and meta-analysis. JAMA Otolaryngol-Head Neck Sur. 2016;142(9):857–65.

    Article  Google Scholar 

  41. Koski L, Ngoma T, Mwaiselage J, Le L, Soliman AS. Changes in the pattern of kaposi’s sarcoma at ocean road cancer institute in Tanzania (2006–2011). Int J STD AIDS. 2015;26(7):470–8.

    Article  PubMed  Google Scholar 

  42. Fatahzadeh M, Schwartz RA. Oral Kaposi’s sarcoma: a review and update. Int J Dermatol. 2013;52(6):666–72.

    Article  PubMed  Google Scholar 

  43. Organization WH. No Title. 2014; http://www.ncbi.nlm.nih.gov/pubmed/26203484.

  44. Suárez A, Valbuena MC, Rey M, Porras de Quintana L. Association of HLA subtype DRB1*0407 in Colombian patients with actinic prurigo. Photodermatol Photoimmunol Photomed. 2006;22(2):55–8.

    Article  PubMed  Google Scholar 

  45. Vega-Memije ME, Mosqueda-Taylor A, Irigoyen-Camacho ME, Hojyo-Tomoka MT, Domínguez-Soto L. Actinic prurigo cheilitis: Clinicopathologic analysis and therapeutic results in 116 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94(1):83–91.

    Article  PubMed  Google Scholar 

  46. Vera Izaguirre DS, Zuloaga Salcedo S, González Sánchez PC, et al. Actinic prurigo: a case-control study of risk factors. Int J Dermatol. 2014;53(9):1080–5.

    Article  PubMed  Google Scholar 

  47. Ross G, Foley P, Baker C. Actinic prurigo. Photodermatol Photoimmunol Photomed. 2008;24(5):272–5.

    Article  PubMed  Google Scholar 

  48. Akintoye SO, Greenberg MS. Recurrent aphthous stomatitis. Dent Clin North Am. 2014;58(2):281–97.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Cui RZ, Bruce AJ, Rogers RS. Recurrent aphthous stomatitis. Clin Dermatol. 2016;34(4):475–81.

    Article  PubMed  Google Scholar 

  50. Chattopadhyay A, Shetty KV. Recurrent aphthous stomatitis. Otolaryngol Clin North Am. 2011;44(1):79–88.

    Article  PubMed  Google Scholar 

  51. Scully C, Mignogna M. Oral mucosal disease: pemphigus. Br J Oral Maxillofac Sur. 2008;46(4):272–7.

    Article  Google Scholar 

  52. Scully C, Paes De Almeida O, Porter SR, de Gilkes JJH. Pemphigus vulgaris: the manifestations and long-term management of 55 patients with oral lesions. Br J Dermatol. 1999;140(1):84–9.

    Article  CAS  PubMed  Google Scholar 

  53. Venugopal SS, Murrell DF. Diagnosis and clinical features of pemphigus vulgaris. Immunol Allergy Clin North Am. 2012;32(2):233–43.

    Article  PubMed  Google Scholar 

  54. Taylor J, McMillan R, Shephard M, et al. World workshop on oral medicine VI: a systematic review of the treatment of mucous membrane pemphigoid. Oral Sur Oral Med Oral Pathol Oral Radiol. 2015;120(2):161–71.

    Article  CAS  Google Scholar 

  55. Alpsoy E. Behçet’s disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions. J Dermatol. 2016;43(6):620–32.

    Article  CAS  PubMed  Google Scholar 

  56. Kalayciyan A, Zouboulis CC. An update on Behҫet’s disease. J Eur Acad Dermatol Venereol. 2007;21(1):1–10.

    Article  CAS  PubMed  Google Scholar 

  57. Lewis KA, Graham EM, Stanford MR. Systematic review of ethnic variation in the phenotype of Behcet’s disease. Scandinavian J Rheumatol. 2007;36(1):1–6.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Dermatology, Boston Medical Center, 609 Albany St. J-202, Boston, MA, 02118, USA

    Mayra B. C. Maymone & Allison R. Larson

Authors
  1. Mayra B. C. Maymone
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  2. Allison R. Larson
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Corresponding author

Correspondence to Allison R. Larson .

Editor information

Editors and Affiliations

  1. Department of Dermatology, Center for Ethnic Skin, Boston University, Boston, Massachusetts, USA

    Neelam A. Vashi

  2. University of California, San Francisco, San Francisco, California, USA

    Howard I. Maibach

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Maymone, M.B.C., Larson, A.R. (2017). Mucosal Lesions in Skin of Color. In: Vashi, N., Maibach, H. (eds) Dermatoanthropology of Ethnic Skin and Hair. Springer, Cham. https://doi.org/10.1007/978-3-319-53961-4_8

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  • DOI: https://doi.org/10.1007/978-3-319-53961-4_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-53960-7

  • Online ISBN: 978-3-319-53961-4

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