Non-inferiority and Equivalence Trials

Reda, Domenic J.

doi:10.1007/978-3-319-53877-8_7

Domenic J. Reda³

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Abstract

The intent of a non-inferiority trial and an equivalence trial is to determine whether an experimental treatment is similar to a control. This is in contrast to a traditional parallel group trial where the objective is to determine whether an experimental treatment differs from a control.

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Authors and Affiliations

Department of Veterans Affairs, Cooperative Studies Program Coordinating Center (151K), Hines VA Hospital, Building 1, Room B240, Hines, IL, 60141, USA
Domenic J. Reda

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Domenic J. Reda
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Correspondence to Domenic J. Reda .

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Editors and Affiliations

Department of Surgery, Boston VA Healthcare System Department of Surgery, West Roxbury, Massachusetts, USA
Kamal M.F. Itani
Depatment of Veteran Affairs, Cooperative Studies Program Coordinating Center, Hines VA Hospital, Hines, Illinois, USA
Domenic J. Reda

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Reda, D.J. (2017). Non-inferiority and Equivalence Trials. In: Itani, K., Reda, D. (eds) Clinical Trials Design in Operative and Non Operative Invasive Procedures. Springer, Cham. https://doi.org/10.1007/978-3-319-53877-8_7

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DOI: https://doi.org/10.1007/978-3-319-53877-8_7
Published: 17 May 2017
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-53876-1
Online ISBN: 978-3-319-53877-8
eBook Packages: MedicineMedicine (R0)

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