Zika in Focus

pp 63-92


Neuroimaging Findings of Congenital Zika Syndrome

  • Maria de Fátima Viana Vasco AragãoAffiliated withMauricio de Nassau UniversityCentro Diagnóstico Multimagem Email author 
  • , Alessandra Mertens Brainer-LimaAffiliated withPROCAPE, Universidade de Pernambuco
  • , Arthur Cesário de HolandaAffiliated withUniversidade Federal de Pernambuco
  • , Natacha Calheiros de Lima PetribuAffiliated withHospital Barão de Lucena

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The imaging and pathological findings in congenital Zika syndrome include moderate and severe microcephaly, in as many as 75% of the cases [1], ophthalmological and auditory abnormalities [2, 3], and arthrogryposis [4]. However, these are not the only abnormalities that can be found, and the complete disease spectrum is still unknown. Some babies are born with head circumference at the lower limit of the normal range, but later progress to microcephaly. In the authors’ experience, they correspond to about 10% of microcephaly cases confirmed with positive IgM CSF (unpublished data). However, the clinical spectrum of the effects of Zika virus infection during pregnancy is not yet known.