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Chemical Composition Effect of Sol-Gel Derived Bioactive Glass Over Bioactivity Behavior

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Proceedings of the 3rd Pan American Materials Congress

Part of the book series: The Minerals, Metals & Materials Series ((MMMS))

Abstract

Bioactive glasses (BG) are a group of inorganic materials widely used in Bone Tissue Engineering (BTE). These biomaterials react with body fluids resulting in the formation of bone like apatite layer. In this study, sol-gel derived bioactive glass was synthesized in the SiO2-CaO-P2O5 system according to augmented constrained mixture experimental design, with percentage restrictions for each oxide as follows: 58 ≤ SiO2 ≤ 70; 6 ≤ P2O5 ≤ 9 and 24 ≤ CaO ≤ 34. BG were conformed into short-bulk cylinders and immersed in Simulated Body Fluid (SBF) solution for 7 and 14 days in order to carry out bioactivity tests. Apatite layer formation was confirmed by Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Analysis (EDX). The results showed apatite layer formation depended on BG chemical composition proved with p-values from ANOVA analysis below 0.05 indicating factors significance over the response. The formed apatite layer presented a Ca/P ratio similar to bone apatite, this result is appropriate for biomaterials used in BTE.

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Acknowledgements

The authors are thankful with Biomaterials Research Group for providing the necessary reagents and studies during the development of this project.

Conflict of Interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Biomaterials Research Group, Engineering Faculty, University of Antioquia, St 70 Nº 52-21, Medellin, Colombia

    L. A. Quintero & D. M. Escobar

Authors
  1. L. A. Quintero
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  2. D. M. Escobar
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Corresponding author

Correspondence to L. A. Quintero .

Editor information

Editors and Affiliations

  1. Dept. of Nanoengineering, MC 0448, University of California-San Diego Dept. of Nanoengineering, MC 0448, LA JOLLA, California, USA

    Marc André Meyers

  2. ESFM-IPN , Mexico City, Mexico

    Hector Alfredo Calderon Benavides

  3. UTN-National University of Technology , Buenos Aires, Argentina

    Sonia P Brühl

  4. Universidad de Antioquia , Medellín, Colombia

    Henry A Colorado

  5. Pratt & Whitney Canada , Longueuil, Canada

    Elvi Dalgaard

  6. Military Institute of Engineering , Rio de Janerio, Brazil

    Carlos Nelson Elias

  7. Universidade Federal de Minas Gerais , Belo Horizonte, Brazil

    Roberto B Figueiredo

  8. Ternium Mexico , Nuevo León, Mexico

    Omar Garcia-Rincon

  9. Division of Materials Sci & Engg, Hanyang University Division of Materials Sci & Engg, Seoul, Korea (Republic of)

    Megumi Kawasaki

  10. Dept. Engineering & the Environment, University of Southampton Dept. Engineering & the Environment, Southampton, United Kingdom

    Terence G. Langdon

  11. University of Concepción , Concepción, Chile

    R.V. Mangalaraja

  12. Universidad Nacional de Ingeniería , Lima, Peru

    Mery Cecilia Gomez Marroquin

  13. Federal University of Rio de Janeiro , Rio de Janeiro, Brazil

    Adriana da Cunha Rocha

  14. Dept Chemical Engg & Sci, University of California, Irvine Dept Chemical Engg & Sci, Irvine, California, USA

    Julie M Schoenung

  15. Universidade Federal Fluminense , Niterói, Brazil

    Andre Costa e Silva

  16. Mechanical Engineering, University of Waterloo Mechanical Engineering, WATERLOO, Ontario, Canada

    Mary Wells

  17. ETH Zurich , Zürich, Switzerland

    Wen Yang

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© 2017 The Minerals, Metals & Materials Society

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Quintero, L.A., Escobar, D.M. (2017). Chemical Composition Effect of Sol-Gel Derived Bioactive Glass Over Bioactivity Behavior. In: Meyers, M., et al. Proceedings of the 3rd Pan American Materials Congress. The Minerals, Metals & Materials Series. Springer, Cham. https://doi.org/10.1007/978-3-319-52132-9_2

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