Addressing the Question: Phototherapy and the Risk of Skin Cancer
Given that UVA and UVB from natural sunlight are known to be carcinogenic to the skin, the main safety question for dermatologists and patients alike is the risk of skin malignancy of phototherapy. UVB phototherapy appears not to have any increased risk of melanoma and nonmelanoma skin cancer. There is evidence of an increased risk of developing non-melanoma skin cancer with more than 250 treatments of PUVA in fair-skinned Caucasian individuals. The risk of genital skin cancers with UVB and PUVA are unclear, and therefore, genital shielding should be routinely practiced.
KeywordsBurning Psoriasis Retinoid
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