Industrial Perspectives Which Have to Be Taken into Account to Scale from the Laboratory to Industry?

Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)


This chapter considers the industrial perspectives available on the topic from the point of view of the authors in terms of the feasibility of a stronger interaction between industry and academia in order to focus the research on the solution of industrial problems.


Solutions Enzyme stability Enzyme activity Enzyme reuse Process configurations Processes costs Multiphasic processes 


  1. 1.
    Tischer W, Wedekind F (1999) Immobilized enzymes: methods and applications toptopics in current chemistry, vol 200. Springer, BerlinGoogle Scholar
  2. 2.
    Guauque Torres P, Foresti ML, Ferreira ML (2013) Cross-linked enzyme aggregates (CLEAs) of lipases: a practical procedure for the calculation of their recovered activity. AMB Express 3(1):1–11CrossRefGoogle Scholar
  3. 3.
    Lassalle V, Pirillo S, Rueda E, Ferreira ML (2011) An accurate UV/visible method to quantify proteins and enzymes: impact of aggregation, buffer concentration and the nature of the standard. Curr Top Anal Chem Res Trend 8:83–93Google Scholar
  4. 4.
    Nielsen PM, Rancke-Madsen A, Holm HC, Burton R (2016) Production of biodiesel using liquid lipase formulations. J Am Chem Soc 93:905–910Google Scholar
  5. 5.
    CLEAs Technologies web page
  6. 6.
    Fattor D (2012) Stability and stabilization of industrial biocatalysts. University of Trieste 2010-2011Google Scholar
  7. 7.
    de Godoy Daiha K, Angeli R, Dias de Oliveira S, Volcan Almeida R (2015) Are lipases still important biocatalysts? A study of scientific publications and patents for technological forecasting. PLoS ONE. doi: 10.1371/journal.pone.0131624.June.25 Google Scholar
  8. 8.
    Anobom CD, Anderson S. Pinheiro, De-Andrade RA, Aguieiras ECG, Andrade GC, Moura MV, Almeida RV, Freire DM (2014), From structure to catalysis: recent developments in the biotechnological applications of lipases, BioMed Res Int 684506, 11Google Scholar
  9. 9.
    Choi JM, Han S, Kim H (2015) Industrial applications of enzyme biocatalysis: current status and future aspects. Biotechnol Adv 33:1443–1454CrossRefGoogle Scholar
  10. 10.
    Vadgam RN, Odaneth AA, Lali AM (2015) Green synthesis of isopropyl myristate in novel single phase medium. Part I: batch optimization studies. Biosci Rep 8:133–137Google Scholar
  11. 11.
    Yang T, Fruekilde M, Xu X (2005) Suppression of acyl migration in enzymatic production of structured lipids through temperature programming. Food Chem 92:101–107CrossRefGoogle Scholar
  12. 12.
    Li S, Yang X, Yang S, Zhu M, Wang X (2012) Technology prospecting on enzymes: application, marketing and engineering. Comput Struct Biotechnol J 2(3):e201209017Google Scholar
  13. 13.
    Kumar A, Dhar K, Singh Kanwar S, Kumar Arora P (2016) Lipase catalysis in organic solvents: advantages and applications. Biol Proced Online 18:2CrossRefGoogle Scholar
  14. 14.
    Borrelli GM, Trono D (2015) Recombinant lipases and phospholipases and their use as biocatalysts for industrial applications. Int J Mol Sci 16:20774–20840CrossRefGoogle Scholar
  15. 15.
    Abdelmoez W, Mustafa A (2014) Oleochemical industry future through biotechnology. J Oleo Sci 63(6):545–554CrossRefGoogle Scholar
  16. 16.
    Hama S, Kondo A (2013) Enzymatic biodiesel production: an overview of potential feedstocks and process development. Bioresour Technol 135:386–395CrossRefGoogle Scholar
  17. 17.
    WooGo A, Sutanto S, Ong LK, Tran-Nguyen PL, Ismadji S, Ju Y (2016) Developments in in-situ (trans) esterification for biodiesel production: a critical review. Renew Sust Energ Rev 60:284–230CrossRefGoogle Scholar
  18. 18.
    Weenen TC, Ramezanpour B, Pronker ES, Commandeur H, Claassen E (2013) Food-pharma convergence in medical nutrition—best of both worlds? PLoS ONE 8(12):e82609CrossRefGoogle Scholar

Copyright information

© The Author(s) 2017

Authors and Affiliations

  1. 1.PLAPIQUI-UNS-CONICETBuenos AiresArgentina

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