Abstract
Most fungi to which we are regularly exposed through the air or because they are part of our normal microbiota do not usually cause disease in immunocompetent individuals. However, some fungi can become pathogenic if host defenses are breached with symptoms ranging from mild superficial infections to severe systemic diseases that are associated with a high degree of morbidity and mortality. Understanding the immune response against fungal infections is of key importance for the development of better preventive and therapeutic options. However, the host response against different fungal infections are as diverse and distinct as the different fungal diseases themselves. Clinical and basic research during the last decade has brought exciting new insights into the pathogenesis of fungi and revealed important molecular and cellular players in host-fungal interactions and host defense. This chapter summarizes and reviews recent advances in the field that have shaped the current understanding of antifungal immunity.
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Altmeier, S., LeibundGut-Landmann, S. (2017). Immunity to Fungal Infections. In: Carvalho, A. (eds) Immunogenetics of Fungal Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-50842-9_2
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