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Peripheral Neuropathy Due to Tuberculosis

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Abstract

The developing countries like India are faced with common health issues like the infectious disease of tuberculosis (TB), caused by bacilli of Mycobacterium tuberculosis. The peripheral nervous system involvement by M. tuberculosis is rare and full of controversies. Many possibilities have been suggested without any definite single causative factor. Causes of peripheral neuropathy (PN) in TB infection include the side effects caused by potent anti-TB drugs (mainly, streptomycin, rifampicin, and ethambutol), immune-mediated PN, vasculitis-related PN, sarcoidosis, leprosy-related neuropathy, compressive neuropathy, and meningitis-related radiculopathy. The causative link of TB infection with PN is rare with few reported cases, of which one is my own study.

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Abbreviations

AFB:

Acid fast bacilli

CBC:

Complete blood count

CD:

Cluster of differentiation

CNS:

Central nervous system

CT:

Computed tomography

EMB:

Ethambutol

EMG:

Electromyography

FNAC:

Fine-needle aspiration cytology

GAN:

Greater auricular nerve

GBS:

Guillain-Barré syndrome

H&E:

Hematoxylin and Eosin

HIV:

Human immunodeficiency virus

IENFD:

Intraepidermal nerve fiber density

INH:

Isoniazid

MRI:

Magnetic resonance imaging

NCS:

Nerve conduction study

PN:

Peripheral neuropathy

PNS:

Peripheral nervous system

PZA:

Pyrazinamide

RIF:

Rifampicin

STR:

Streptomycin

TB:

Tuberculosis

TSH:

Thyroid-stimulating hormone

USG:

Ultrasonography

ZN:

Ziehl-Neelsen

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Authors and Affiliations

  1. Department of Pathology, B.K.L. Walawalkar Rural Medical College, Shreekshetra Dervan, Kasarwadi, At post-Sawarde, Chiplun, District-Ratnagiri, 415606, Maharashtra, India

    Bhushan Malhari Warpe MBBS, MD,DNB (Pathology)

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  1. Bhushan Malhari Warpe MBBS, MD,DNB (Pathology)
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Correspondence to Bhushan Malhari Warpe MBBS, MD,DNB (Pathology) .

Editor information

Editors and Affiliations

  1. Adnan Menderes University, School of Medicine, Aydın, Turkey

    Mehmet Turgut

  2. Mohammed V University in Rabat, Avicenne Military Hospital of Marrakech, Rabat, Morocco

    Ali Akhaddar

  3. Hacettepe University, School of Medicine, Ankara, Turkey

    Ahmet T. Turgut

  4. King George Medical University, Lucknow, Uttar Pradesh, India

    Ravindra K. Garg

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Warpe, B.M. (2017). Peripheral Neuropathy Due to Tuberculosis. In: Turgut, M., Akhaddar, A., Turgut, A., Garg, R. (eds) Tuberculosis of the Central Nervous System. Springer, Cham. https://doi.org/10.1007/978-3-319-50712-5_23

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  • DOI: https://doi.org/10.1007/978-3-319-50712-5_23

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-50711-8

  • Online ISBN: 978-3-319-50712-5

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