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Magnetic Nanoparticles as Drug Delivery Devices

  • Mariela A. Agotegaray
  • Verónica L. Lassalle
Chapter
Part of the SpringerBriefs in Molecular Science book series (BRIEFSMOLECULAR)

Abstract

Nano-size in combination with magnetic properties gave rise to novel nanomaterials with improved properties, especially with regard to biomedical applications. This chapter is devoted to show the strong relationship between the design of nanoparticles and the final properties able to define its efficiency to the desired applications.

According to the literature, several inorganic materials may be chosen to assess magnetic nanodevices, however the iron oxides, such as magnetite and maghemite, are the preferred for several reasons. The property of superparamagnetism becomes crucial when the practical implementation of these nanosystems is intended in the biomedical field. This, and other properties strongly linked to the efficiency in biomedical applications are defined during the synthetic pathways. The most common preparative methods are here described highlighting the advantages and disadvantages as well as the properties of the obtained magnetic nanoparticles.

Coating of magnetic cores is strictly necessary to assess the interest and specific properties required for biomedical uses. In this regard, a classification of the most useful coatings is included highlighting the properties conferred by the selected coating material.

Characterization techniques able to evaluate the size, surface charge, functionality, and magnetism were also reported as a guide.

Keywords

Superparamagnetism Co-precipitation Microemulsion Size Shape 

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Copyright information

© The Author(s) 2017

Authors and Affiliations

  • Mariela A. Agotegaray
    • 1
  • Verónica L. Lassalle
    • 1
  1. 1.INQUISUR – CONICETUniversidad Nacional del SurBahía BlancaArgentina

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